Physiopathological Implications of 7TM Receptors

• Authors: Adam I. Cygankiewicz
• Languages of publication: EN

Abstracts

EN

Seven-transmembrane (7TM) receptors are one of the most important proteins involved in perception of extracellular stimuli and regulation of variety of intracellular signaling pathways. Divergence of receptor types, their ligands and signaling pathways makes 7TM receptors important factors in pathology of many diseases. This review focused on the main diseases in which involvement of 7TM receptors was established e.g., retinitis pigmentosa, severe obesity, and dwarfism. Recent findings of aberrant expression of 7TM receptors in development of cancer were also summarized.

Keywords

EN

Seven-transmembrane receptors; G protein coupled receptors; pathology; cancer

• Publisher: Wydawnictwo Uniwersytetu Łódzkiego
• Journal: Acta Universitatis Lodziensis. Folia Biologica et Oecologica
• Year: 2010
• Volume: 6
• Pages: 33-47

Dates

published

2010-12-04

Contributors

author

Adam I. Cygankiewicz

Identifiers

DOI

10.2478/v10107-009-0005-2