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2014 | 16 | 4 | 15–26

Article title

A comparison of a single genetic factor, two stress factors, and one psychosocial coping factor as predictors of depression in an Australian community sample

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EN

Abstracts

EN
Aim. Although both have shown significant effects upon depression in clinical samples, no direct comparison has been reported of the relative power of psychological resilience and the short form of the serotonin transporter gene 5-HTTLPR as predictors of depression in a community sample. material and methods. In a sample set by a priori power analysis, 67 adult females and 59 adult males were used to enable a comparison between a single genetic factor, childhood stressors, recent stressors, psychological resilience and depression. Results. None of genotype, childhood or recent stressors was significantly associated with depression scores, but resilience was a significant inverse predictor of depression scores and also of the presence of clinically significant depression. discussion. These data suggest that measures of an individual's ability to resist or recover from stress may be useful in assessing vulnerability to depression when used with 'at risk' individuals in everyday practice.

Keywords

Discipline

Year

Volume

16

Issue

4

Pages

15–26

Physical description

Dates

published
2014

References

  • 1. Bosker F, Hartman C, Nolte I, Prins B, Terpstra P, Posthuma D, et al. Poor replication of candidate genes for major de- pressive disorder using genome-wide association data. Mo- lecular Psychiatry. 2011; 16: 516-532.
  • 2. Shyn S, Shi J, Kraft J, Potash J, Knowles J, Weissman M, et al. Novel loci for major depression identified by genome- wide association study of sequenced treatment alternatives to releive depression and meta-analysis of three studies. Mo- lecular Psychiatry. 2011; 16: 202-215.
  • 3. Shi J, Potash J, Knowles J, Weissman M, Coryell W, Scheftner W, et al. Genome-wide association study of recurrent early-onset major depressive disorder. Molecular Psychia- try. 2011; 16: 193-201.
  • 4. Consortium MDDWGotPG. A mega-analysis of genome-wide association studies for major depressive disorder. Molecular Psychiatry. 2012.
  • 5. Grabe H, Schwahn C, Appel K, Mahler J, Schulz A, Spitzer C, et al. Update on the2005 paper: moderation of mental and physical distress by polymorphisms in the 5-HT transporter gene by interacting with social stressors and chronic disease burden. Molecular Psychiatry. 2011; 16: 354-361.
  • 6. Caspi A, Hariri AR, Holmes A, Uher R, Moffitt TE. Genetic Sensitivity to the Environment: The Case of the Serotonin Transporter Gene and Its Implications for Studying Complex Diseases and Traits. American Journal of Psychiatry. 2010; 167(5): 509-527.
  • 7. Caspi A, Sugden K, Moffitt TE, Taylor A, Craig IW, Harrington H, et al. Influence of Life Stress on Depression: Modera- tion by a Polymorphism in the 5-HTT Gene. Science. 2003; 301(5631): 386-389.
  • 8. Hauser J, Leszczynska A, Samochowiec J, Czerski P, Os- tapowicz A, Chliopocka M, et al. Association analysis of the insertion/deletion polymorphism in serotonin transporter gene in patients with affective disorder. European Psychiatry. 2003; 18: 129-132.
  • 9. Karg K, Burmeister M, Shedden K, Sen S.The serotonin transporter promoter variant (5-HTTLPR), stress, and de- pression meta-analysis revisited. Archives of General Psy- chiatry. 2011; 68: 444-454.
  • 10. Sharpley C, Palanisamy S, Glyde N, Dillingham P, Agnew L.An update of the interaction between the serotonic trans- porter promoter variant (5-HTTLPR), stress and depression, plus an exploration of non-confirming findings. Behavioural Brain Research. 2014; 273: 89-105.
  • 11. Chipman P, Jorm A, Prior M, Sanson A, Smart D, Tan X, et al. No interaction between the serotonin transporter polymor- phism (5-HTTLPR) and childhood adversity or recent stress- ful life events on symptoms of depression. American Journal of Medical Genetics. 2007;144B: 561-565.
  • 12. Zhang K, Xu Q, Xu Y, Yang H, Luo J, Sun Y, et al. The com- bined effects of the 5-HTTLPR and 5-HTR1A genes modu- lates the relationship between negative life events and ma- jor depressive disorder in a Chinese population. Journal of Affective Disorders. 2009; 114: 224-231.
  • 13. Fredrickson B, Tugade M, Waugh C, Larkin G. A prospec- tive study of resilience and emotions following the terrorist at- tacks on the United States on September 11th, 2002. Journal of Personality and Social Psychology. 2003; 84: 365-376.
  • 14. Luthar S, Cicchetti D.The construct of resilience: Implica- tions for interventions and social policies. Development and Psychopathology. 2000; 12: 857-885.
  • 15. Charney DS. Psychobiological Mechanisms of resilience and Vulnerability: Implications for Successful Adaptation to Ex- treme Stress. Focus. 2004; 2(3): 368-391.
  • 16. Brooks R.The power of parenting. In: Brooks R, Goldstein S, editors. Handbook of resilience in children New York: Klu- wer Academic/Plenum; 2005. p. 297-314.
  • 17. Tedeschi R, Kilmer R.Assessing strengths, resilience, and growth to guide clinical interventions. Professional Psychol- ogy: Research and Practice. 2005; 36: 230-237.
  • 18. Alvord M, Grados J.Enhancing resilience in children: A proactive approach. Professional Psychology: Research and Practice. 2005; 36: 238-245.
  • 19. Bonanno GA, Galea S, Bucciarelli A, Vlahoz D.What pre- dicts psychological resilience after disaster? The role of de- mographics, resources, and life stress. Journal of Consulting and Clinical Psychology. 2007; 75: 671-682.
  • 20. Jopp D, Rott C.Adaptation in Very Old Age: Exploring the Role of Resources, Beliefs, and Attitudes for Centenarians’ Happiness. Psychology and Aging. 2006; 21(2): 266-280.
  • 21. Karoly P, Reuhlman L.Psychological resilience and its cor- relates in chronic pain. Pain. 2006; 123: 90-97.
  • 22. Watt N, David J, Ladd K, Shamos S.The life course of psy- chological resilience: A phenomenological perspective on de- flecting life’s slings and arrows. The Journal of Primary Pre- vention. 1995; 15: 209-246.
  • 23. Bergstrom A, Jayatissa M, Thykjaer T, Wiborg O.Molecular Pathways Associated with Stress Resilience and Drug Re- sistance in the Chronic Mild Stress Rat Model of Depression - a Gene Expression Study. J Mol Neurosci. 2007; 33(2): 201-215.
  • 24. Feder A, Nestler EJ, Charney DS. Psychobiology and mo- lecular genetics of resilience. Nature Reviews Neuroscience. 2009; 10: 446-457.
  • 25. Cicchetti D, Blender JA. A Multiple-Levels-of-Analysis Per- spective on Resilience. Annals of the New York Academy of Sciences. 2006; 1094: 248-258.
  • 26. Haglund MEM, Nestadt PS, Cooper NS, Southwick SM, Charney DS. Psychobiological mechanisms of resilience: Relevance to prevention and treatment of stress-related psy- chopathology. Development and Psychopathology. 2007; 19: 889-920.
  • 27. Stein M, Campbell-Sills L, Gelernter J.Genetic variation in 5HTTLPR is associated with emotional resilience. American Journal of Medical Genetics B: Neuropsychiatric Genetics. 2009; 150B: 900-906.
  • 28. Carli V, Mandelli L, Zaninotti L, Roy A, Recchia L, Stoppia L, et al. A protective genetic variant for adverse environments? The role of childhood traumas and serotonic transporter gene on resilience and depressive severity in a high-risk popula- tion. European Psychiatry. 2011; 26: 471-478.
  • 29. O’Hara R, Marcus P, Thompson W, Flourney J, Vahia I, Lin X, et al. 5-HTTLPR short allele, resilience, and successful aging in older adults. The American Journal of Geriatric Psychiatry.
  • 30. Hovens J, Giltay E, Wiersma J, Spinhoven P, Penninx B, Zitman F.Impact of childhood life events and trauma on the course of depressive and anxiety disorders. Acta Psychiatri- ca Scandinavia. 2012; 126: 198-207.
  • 31. Judd L, Paulus M, Wells K, Rapaport M.Socioeconomic bur- den of subsyndromal depressive symptoms and major de- pression in a sample of the general population. American Journal of Psychiatry. 1996; 163: 1411-1417.
  • 32. Judd L, Akiskal H, Maser J, Zeller P, Emdicott J, Coryell W, et al. A prospective 12-yar study of subsyndromal and syndro- mal depressive symptoms in unipolar major depressive dis- orders. Archives of General Psychiatry. 1998; 55: 694-700.
  • 33. Lyness J, Heo M, Datto C, Ten Have T, Katz I, Drayer R, et al. Outcomes of Minor and Subsyndromal Depression among Elderly Patients in Primary Care Settings. Annals of Internal Medicine. 2006; 144(7): 496-504.
  • 34. Chopra M, Zubritsky C, Knott K, Have T, Hadley T, Coyne J, et al. Importance of subsyndromal symptoms of depression in elderly patients. The American Journal of Geriatric Psychi- atry. 2005; 13: 597-606.
  • 35. Lyness J, Kim J, Tang W, Tu X, Conwell Y, King D, et al. The clinical significance of subsyndromal depression in oldre pri- mary care patients. American Journal of Geriatric Psychia- try. 2007; 15: 214-223.
  • 36. da Silva Lima A, de Almeida Fleck M.Subsyndromal depres- sion: An impact on quality of life? Journal of Affective Disor- ders. 2007; 100: 163-169.
  • 37. Zung W.A self-rating depression scale. Archives of General Psychiatry1965; 12: 63-70.
  • 38. APA. Diagnostic and Statistical Manual of Mental Disorders (4th ed, Text Revision). Washington, DC: American Psychi- atric Association; 2000.
  • 39. DeJonge J, Baneke J.The Zung Self-rating Depression Scale: A replication study on reliability, validity and predic- tion. Psychological Reports. 1989; 833-834.
  • 40. Gabrys J, Peters K.Reliability, discriminant and predictive validity of the Zung Self-Rating Depression Scale. Psycho- logical Reports. 1985; 57: 1091-1096.
  • 41. Schaefer A, Brown J, Watson C, Plenel D, DeMotts J, Howard M, et al. Comparison of the validities of the Beck, Zung and MMPI depression scales. Journal of Consulting and Clinical Psychology. 1985; 53: 415-418.
  • 42. Sharpley C, Rogers H.Naïve versus sophisticated item-writ- ers for the assessment of anxiety. Journal of Clinical Psychol- ogy. 1985; 41: 58-62.
  • 43. Agrell B, Dehlin O.Comparison of six depression scales in geriatric stroke patients. Stroke. 1989; 20: 1190-1194.
  • 44. Zung W.From art to science: The diagnosis and treatment of depression. Archives of General Psychiatry. 1973; 29: 328-337.
  • 45. Felitti VJ, Anda RF, Nordenberg D, Williamson DF, Spitz AM, Edwards V, et al. Relationship of childhood abuse and house- hold dysfunction to many of the leading causes of death in adults. American journal of preventive medicine. 1998; 14(4): 245-258.
  • 46. Straus MA, Gelles RJ, Smith C.Physical violence in Amer- ican families: Risk factors and adaptations to violence in 8,145 families: Transaction Pub; 1995.
  • 47. Bernstein DP, Fink L, Handelsman L, Foote J.Initial reliabili- ty and validity of a new retrospective measure of child abuse and neglect. The American Journal of Psychiatry; The Amer- ican Journal of Psychiatry. 1994.
  • 48. Wyatt GE. The sexual abuse of Afro-American and white- American women in childhood. Child abuse & neglect. 1985; 9(4): 507-519.
  • 49. Wingenfeld K, Schäfer I, Terfehr K, Grabski H, Driessen M, Grabe H, et al. [The reliable, valid and economic assess- ment of early traumatization: first psychometric characteris- tics of the German version of the Adverse Childhood Experi- ences Questionnaire (ACE)]. Psychotherapie, Psychosoma- tik, medizinische Psychologie. 2011;61(1):e10.
  • 50. Sharpley C, Tanti A, Stone J, Lothian P.The ‘Effects of Life Events’ Inventory. Counselling Psychology Quarterly. 2004; 17: 45-52.
  • 51. Sarason IG, Johnson JH, Siegel JM. Assessing the impact of life changes: development of the Life Experiences Sur- vey. Journal of Consulting and Clinical Psychology; Journal of Consulting and Clinical Psychology. 1978; 46(5): 932.
  • 52. Paykel ES, Myers JK, Dienelt MN, Klerman GL, Lindenthal JJ, Pepper MP. Life events and depression: A controlled study. Archives of General Psychiatry. 1969; 21(6): 753.
  • 53. Holmes TH, Rahe RH. The social readjustment rating scale. Journal of psychosomatic research. 1967.
  • 54. Tennant C, Andrews G. A scale to measure the stress of life events. Australasian Psychiatry. 1976;10(1): 27-32.
  • 55. Heam R, Arlbaster K.DNA extraction techniques for use in education. Biochemistry and Molecular Biology Education. 2010;38: 161-166.
  • 56. Wendland J, Martin B, Kruse M, Lesch K-P, Murphy D.Simul- taneous genotyping of four functional loci of human SLC6A4, with a reappraisal of 5-HTTLPR and rs25531. Molecular Psy- chiatry. 2006; 11: 224-226.
  • 57. Bossini L, Casolaro I, Caterini C, Koukouna D, Fortini V, Cec- chini F, et al. Diagnostic mistakes in post-traumatic sterss disorder. The problem of symptom overlap with depression. Psychiatr Pol. 2013; 47: 1051-1063.
  • 58. Folsom T, Fatemi H.The involvement of Reelin in neurode- velopmental disorders. Neuropharmacology. 2012.
  • 59. Borowieka-Kluza J, Miernik-Jaeschke M, Jaeschke R, Si- wek M, Dudek D.The affective disorder-related burden im- posed on the family environment: an overview. Psychiatr Pol. 2013;XLVII: 635-644.

Document Type

article

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YADDA identifier

bwmeta1.element.psjd-1509-2046-2014-16-4-15
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