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Journal
1995 | 43 | 3-4 | 161-167
Article title

Kinetics of organophosphorus pesticide inhibition of acetylcholinesterase (E.C.3.1.1.7) from the head of Tryporyza nivella (Fabr.) (Lepidoptera:Pyralidae)

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EN
Abstracts
EN
Kinetic constans(Kd, k2 and ki values) for the inhibition of the Tryporyza nivella head acetylcholinesterase (ChE)by organophosphorus (Trichlorfon, Malaoxon and Diazoxon) pesticides were determined in vitro.These compounds showed a high affinity for AChE and the affinity constans (Kd).There was a little variation among the phosphorylation constans (K2), indicating a minor role for the phosphorylation step in the inhibition process.The significant variation of the molecular reaction (ki) of these compounds could be attributed to variation in the Kd rather than to the K2.Trichlorfon, having a higher ki value, was found to be less toxic than Malaoxan and Diazoxon.
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Journal
Year
Volume
43
Issue
3-4
Pages
161-167
Physical description
Contributors
author
References
Document Type
article
Publication order reference
G.Pandey
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-fbebd031-b83b-3384-bf72-2dc944a7ac2e
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