PL EN


Preferences help
enabled [disable] Abstract
Number of results
2002 | 56 | 3 | 293-305
Article title

The effect of changes in extracellular pH on neuronal GABAA receptors

Title variants
Languages of publication
PL
Abstracts
EN
Local pH values of both intra- and extracellular liquids can be regulated by a number of mechanisms including membrane transport and metabolism. It is known that the changes of extracellular pH accompanying physiological and pathological processes are sufficient to affect several important structures such as ionic channels, transporters, receptors etc. In particular, several reports indicate that GABAA receptor is strongly modulated by this factor. The effect of pH application of ultrafast perfusion system allowed to explore the mechanisms of pH effect on GABAA receptors in neurons. It is concluded that changes in pH exert their effects by allosteric modulation of GABAA receptors.
Keywords
Publisher

Year
Volume
56
Issue
3
Pages
293-305
Physical description
Contributors
author
author
References
Document Type
ARTICLE
Publication order reference
E.D. Zarnowska, Katedra i Zaklad Biofizyki AM, ul. Chalubinskiego 10, 50-368 Wroclaw, Poland
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-e3e47cb6-ecdb-3b30-83c7-2028b846675c
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.