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1993 | 45 | 1 | 75-82
Article title

Rennin inhibitors containinig statine and 6-aminohexanoic acid. Part III

Content
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Languages of publication
EN
Abstracts
EN
Five peptide renin inhibitors were synthesized and their potency was assayed in vitro by a spectrofluorometric method (assay of Leu-Val-Tyr-Ser released from N-acetyltetradecapeptide substrate by renin in the presence of an inhibitor). Their stability was tested by assay of Phe and Pro-Phe released after incubation with chymotrypsin. The most potent inhibitor was Boc-Phe-His-Sta-epsilonAhx-OME, the most stable - Boc-Pro-Phe-His-Sta-epsilonAhx-OME (resistant to incubation with chymotrypsin for 4 h).
Year
Volume
45
Issue
1
Pages
75-82
Physical description
References
Document Type
article
Publication order reference
Ryszard Paruszewski
YADDA identifier
bwmeta1.element.element-from-psjc-d2a65158-5676-3ce2-bfef-84ae86028a03
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