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2006 | 54 | 3 | 173-175
Article title

Modulation of apoptosis signaling for cancer therapy

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Languages of publication
EN
Abstracts
EN
Apoptosis, the cell's intrinsic death program, plays a central role in regulating tissue homeostasis. Also, most cytotoxic therapies used for cancer treatment, such as chemotherapy, g-irradiation, suicide genes, or immunotherapy, predominantly act by triggering apoptosis in target cells. Thus, understanding the molecular events that regulate apoptosis and how tumor cells evade apoptotic deletion have provided a paradigm to link cancer genetics and response to cancer therapy. Therefore, insights into the mechanisms regulating drug-induced apoptosis provide rational targets for novel therapeutic interventions.
Keywords
Publisher

Year
Volume
54
Issue
3
Pages
173-175
Physical description
Contributors
author
author
References
Document Type
REVIEW
Publication order reference
Simone Fulda, Ph.D., University Children?s Hospital, Eythstr. 24, D-89075 Ulm, Germany
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-cdf91d9c-cfc4-3421-9422-2c391ba825b9
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