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2002 | 50 | 2 | 105-110
Article title

Significance of tumor cell ? receptors in human cancer

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EN
Abstracts
EN
Every tumor cell is equipped with an array of biologically active surface molecules, and several these function as receptors for various ligands. They include MHC, or in the case of humans, HLA antigens, cytokine receptors, cell-adhesion molecules, growth factor receptors, Fas/Fas-ligand molecules and others. Their expressions are a subject to alterations, usually to the advantage of tumor growth and spread. Some appear on tumor cells de novo, having no counterparts on the respective normal cells. Detailed knowledge about the expression of tumor-cell receptors and their genotypes, in particular of cancerous ones, may provide information essential for the creation of tools for specific tumor immunotherapy.
Publisher

Year
Volume
50
Issue
2
Pages
105-110
Physical description
Contributors
author
References
Document Type
REVIEW
Publication order reference
J. Zeromski, Chair and Department of Clinical Immunology, Karol Marcinkowski University of Medical Sciences, Przybyszewskiego 49, 60-355 Poznan, Poland
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YADDA identifier
bwmeta1.element.element-from-psjc-b13d5580-f24e-3995-953e-ff27436a48c4
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