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1996 | 56 | 3 | 753-756
Article title

Biosythesis of gonadotropins in vivo

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EN
Abstracts
EN
GnRh is potent stimulator of gonadotropin's alpha and beta chains synthesis in vivo.Stimulation of LH-beta gene transcription requires pulsatile GnRH administration but the transcription of alpha subunit can be stimulated independently of GnRH mode of administration.Castration increases whereas in vivo estradiol and testostrone replacement decreases the rate of gene transcription of pituitary gonadotropin subunits.Thyroid hormones can enhance or diminsh the pituitery levels of LH-beta and FSH-beta subunit mRNAs in female rats.Inhibin activin and follistatin were shown to be potent regulators of FSH-beta gene expression.
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Year
Volume
56
Issue
3
Pages
753-756
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author
author
References
Document Type
review
Publication order reference
K.Kochman
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YADDA identifier
bwmeta1.element.element-from-psjc-a0ab796c-2be8-392f-bde6-5b1dd262201a
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