Characterization of NO and cytokine release by transplantable melanoma cell lines in relationship to their differentiation
Languages of publication
Changes in the secretory activity of two transplantable melanoma lines (differing in many biological features) as regards nitric oxide (NO) and interleukin 6 (IL-6), tumor necrosis factor (TNF-), oncostatin M (OSM) secretion were the subject of the present study. Obtained results show that a spontaneous alteration of the hamster?s native melanoma line in to an amelanotic one is accompanied by a global change of the secretory activity but there was not distinct correlation between the endogenous cytokine secretion and NO secretion by cells of both melanoma lines.
Publication order reference
K. Kozlowska, Department of Embryology, Medical University of Gdansk, Debinki 1, 80-211 Gdansk, Poland