Characterization of NO and cytokine release by transplantable melanoma cell lines in relationship to their differentiation

• Authors: K. Kozlowska , M. Zarzeczna , M. Cichorek
• Languages of publication: EN

Abstracts

EN

Changes in the secretory activity of two transplantable melanoma lines (differing in many biological features) as regards nitric oxide (NO) and interleukin 6 (IL-6), tumor necrosis factor (TNF-), oncostatin M (OSM) secretion were the subject of the present study. Obtained results show that a spontaneous alteration of the hamster?s native melanoma line in to an amelanotic one is accompanied by a global change of the secretory activity but there was not distinct correlation between the endogenous cytokine secretion and NO secretion by cells of both melanoma lines.

Keywords

EN

INTERLEUKIN 6; INTERLEUKIN-6; MELANOMA; ONCOSTATIN M; TUMOR NECROSIS FACTOR

Discipline

• IMMUNOLOGY: IMMUNOLOGY

• Publisher: Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences
• Journal: Archivum Immunologiae et Therapiae Experimentalis
• Year: 2001
• Volume: 49
• Issue: 2 suppl.
• Pages: 103

Contributors

author

K. Kozlowska

author

M. Zarzeczna

author

M. Cichorek

• Document Type: ARTICLE
• Publication order reference: K. Kozlowska, Department of Embryology, Medical University of Gdansk, Debinki 1, 80-211 Gdansk, Poland