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Number of results
2001 | 49 | 3 | 195-201
Article title

Peptide loading of nascent MHC class i molecules

Content
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Languages of publication
EN
Abstracts
EN
A critical molecular interaction during assembly of the major histocompatibility complex (MHC) class I molecules takes place between the heavy chain and the transporter-associated with antigen-processing (TAP) complex. The recent mapping of regions of the heavy chain involved in the binding to TAP suggests a complex molecular interaction essential for the cell surface expression of the MHC class I. The advances made in understanding the TAP-MHC class I interaction are reviewed and discussed here.
References
Document Type
REVIEW
Publication order reference
S. Vukmanovic, Michael Heidelberger Division of Immunology, Department of Pathology, and Kaplan Coprehensive Cancer Center, NYU School of Medicine, 550 First Avenue, New York, NY 10016, USA
YADDA identifier
bwmeta1.element.element-from-psjc-2fe06f0d-c841-328e-837a-4cbad4a48d81
Identifiers
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