PL EN


Preferences help
enabled [disable] Abstract
Number of results
2002 | 56 | 6 | 757-777
Article title

Polyamines and their role in tumour growth

Title variants
Languages of publication
PL
Abstracts
EN
The polyamines - putrescine, spermidine and spermine - are normal constituents of prokariotic and eukariotic cells. These small polycationic, aliphatic compounds are essential for normal cell proliferation. Cells cease to proliferate, when they are depleted of their polyamines, but resume a normal growth rate after supplementation with these compounds. Because of the sustained increase in polyamine biosynthesis in preneoplastic and neoplastic tissues, a great deal of interest has been given to the polyamine biosynthesis, network and uptake systems as a target in antineoplastic strategies.
Keywords
Publisher

Year
Volume
56
Issue
6
Pages
757-777
Physical description
Contributors
References
Document Type
ARTICLE
Publication order reference
J. Godlewski, Instytut Chemii Organicznej, Biochemii i Biotechnologii, Politechnika Wroclawska, Wybrzeze Wyspianskiego 29, 50-370 Wroclaw, Poland
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-1eea16b4-0087-332c-abb3-5672f7e92697
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.