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1997 | 51 | 5 | 531-546
Article title

Immunopathology of Grave's disease

Title variants
Languages of publication
PL
Abstracts
EN
The pathogenesis Graves' disease, an autoimmune disorder, is not fully understood. Immune disturbances, genetic predisposition and environmental factors, affecting thyroid gland, appear to play the main role in contribution and development of the disease. Autoreactive T lymphocyte infiltrates in the thyroid gland and/or in the retroorbital tissues and autoantibodies to TSH receptor detected in almost all of the patients, have been considered to be responsible for hyperthyroidism, ophtalmopathy, pretibial dermopathy and goiter. In this review, we describe some recent reports on the pathophysiological and immunological aspects of the thyroidal and extrathyroidal manifestations of the Graves' disease.
Keywords
Year
Volume
51
Issue
5
Pages
531-546
Physical description
Contributors
author
author
author
References
Document Type
article
Publication order reference
Z. Baj, Zaklad Tyreologii Instytutu Endokrynologii AM, ul. Sterlinga 5, 91-425 Lodz, Poland
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-193177a7-169b-3466-97e2-6671eed83573
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