Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl

PL EN


Preferences help
enabled [disable] Abstract
Number of results
1992 | 30 | 2 | 133-146

Article title

Neuropathological changes in resected temporal lobe of patients with cryptogenic epilepsy

Title variants

Languages of publication

EN

Abstracts

EN
The study was performed on cerebral tissue resected during temporal lobectomy in 16 patients whose long-standing cryptogenic epilepsy did not submit to anticonvulsive drugs. Cases presenting definite etiological factors such as CNS trauma, infection or neoplasm were excluded. Neuropathological investigations disclosed microangiomas and focal vascular malformations in the meninges and tissue in 7 patients. Neuronal heterotopias in the white matter and of the white matter in the cortex were observed in 3 cases, Main cortical changes were: neuronal loss,chronic neuronal degeneration, perineuronal satellitosis, and GFAP-positive submeningeal gliosis, especially at the bottom of sulci, perivascular gliosis and laminar or diffuse gliosis. the changes in the hippocamus were most enhanced in the end-plate and in the sector H3 of the pyramidal layer. Astrocytic gliosis in the white matter presented distinct GFAP and S-100 immunostaining; the latter involved in some cases a wider area than the GFAP reaction. The above named changes are analysed with regard to the presumed epileptogenic factors and to the postepileptic damage.

Keywords

References

Document Type

article

Publication order reference

Halina Kroh

Identifiers

YADDA identifier

bwmeta1.element.element-from-psjc-0c712e2b-ce3e-36a9-8dbb-9dd02da46af0
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.