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Number of results
2019 | 76 | 1 | 67-73
Article title

Bioavailability of mesalazine from two coated formulation tablets

Content
Title variants
Languages of publication
EN
Abstracts
EN
HPLC methodology with a fluorescent detector is suitable for bioavailability studies of investigated generic tablets Mesalazine 250 mg (Jelfa, Poland) versus standard Salofalk tablets (Dr. Falk, Germany). The investigations were completed in ten healthy subjects in a double way crossover design. Only one bioavailability parameter – time for maximum mesalazine plasma concentration (tmax ) and overall elimination rate constants are significantly greater for the above standard tablets. The parameters like maximum plasma drug concentration (Cmax), lag time for absorption (Tlag), biological half-life time (t1/2 ) are also more favorable for the standard, but these values are not significantly different.
Year
Volume
76
Issue
1
Pages
67-73
Physical description
Dates
published
2019-02-28
Contributors
References
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.doi-10_32383_appdr_92604
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