PL EN


Preferences help
enabled [disable] Abstract
Number of results
2011 | 119 | 1 | 84-87
Article title

Possible Causes of Asymmetry in the Mössbauer Spectra of~Brain Tissue

Content
Title variants
Languages of publication
EN
Abstracts
EN
Iron present in the human brain plays important role in neurodegenerative diseases like Parkinson and Alzheimer diseases. Brain iron is mainly stored within globular protein called ferritin. Mössbauer spectra of brain tissue are asymmetric doublets at 300 K and 90 K. This asymmetry is slightly bigger in the case of samples taken from diseased subjects. Reason for this is still unknown. Few possible causes of aforesaid difference had been discussed. Nanometer-size of ferritin iron cores, pathological protein influence were taken into account. It was also discussed if experimentally available statistics is sufficient to obtain reliable asymmetry coefficient from Mössbauer spectra. Physical experiment were reproduced by means of computer simulations. Nevertheless, the reason for the asymmetry has not been completely elucidated yet.
Keywords
EN
Publisher

Year
Volume
119
Issue
1
Pages
84-87
Physical description
Dates
published
2011-01
Contributors
author
  • Faculty of Physics, Warsaw University of Technology, Koszykowa 75, 00-662 Warszawa, Poland
  • Faculty of Physics, Warsaw University of Technology, Koszykowa 75, 00-662 Warszawa, Poland
References
  • 1. J. Gałązka-Friedman, E.R. Bauminger, A. Friedman, Hyperfine Interact. 141/142, 267 (2002)
  • 2. J. Gałązka-Friedman, E.R. Bauminger, D. Koziorowski, A. Friedman, Biochim. Biophys. Acta 1688, 130 (2004)
  • 3. J. Gałązka-Friedman, E.R. Bauminger, K. Szlachta, K. Schweitzer, Z. Wszolek, D. Dickson, A. Friedman, Acta Phys. Pol. A 115, 545 (2009)
  • 4. W.H. Press, S.A. Teukolsky, W.T. Vetterling, B.P. Flannery, Numerical Recipes in C The Art of Scientific Computing, Second Edition, Cambridge University Press, Cambridge 2002
  • 5. http://www.isapps.ca/recoil/
  • 6. E. Murad, U. Schwarzmann, Am. Mineral. 65, 1044 (1980)
  • 7. C. Quintana, L. Gutierrez, Biochim. Biophys. Acta 1800, 770 (2010)
  • 8. J.L. Lambor, J. Puziewicz, Am. Mineral. 75, 431(1990)
  • 9. G.C. Papaefthymiou, Biochim. Biophys. Acta 1800, 886 (2010)
  • 10. J. Gałązka-Friedman, Hyperfine Interact. 189, 31 (2009)
  • 11. J.M. Cowley, D.E. Janney, R.C. Gerkin, P.R. Buseck, J. Struct. Biol. 131, 210 (2000)
  • 12. J. Gałązka-Friedman, E.R. Bauminger, A. Friedman, M. Barcikowska, D. Hechel, I. Nowik, Mov. Disord. 11, 8 (1996)
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-appv119n124kz
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.