Possible Causes of Asymmetry in the Mössbauer Spectra of~Brain Tissue

• Authors: K. Szlachta , J. Gałązka-Friedman
• Languages of publication: EN

Abstracts

EN

Iron present in the human brain plays important role in neurodegenerative diseases like Parkinson and Alzheimer diseases. Brain iron is mainly stored within globular protein called ferritin. Mössbauer spectra of brain tissue are asymmetric doublets at 300 K and 90 K. This asymmetry is slightly bigger in the case of samples taken from diseased subjects. Reason for this is still unknown. Few possible causes of aforesaid difference had been discussed. Nanometer-size of ferritin iron cores, pathological protein influence were taken into account. It was also discussed if experimentally available statistics is sufficient to obtain reliable asymmetry coefficient from Mössbauer spectra. Physical experiment were reproduced by means of computer simulations. Nevertheless, the reason for the asymmetry has not been completely elucidated yet.

Keywords

EN

87.64.kx

Discipline

• 87.64.kx: Mössbauer

• Publisher: Institute of Physics, Polish Academy of Sciences
• Journal: Acta Physica Polonica A
• Year: 2011
• Volume: 119
• Issue: 1
• Pages: 84-87

Dates

published

2011-01

Contributors

author

K. Szlachta

• Faculty of Physics, Warsaw University of Technology, Koszykowa 75, 00-662 Warszawa, Poland

author

J. Gałązka-Friedman

• Faculty of Physics, Warsaw University of Technology, Koszykowa 75, 00-662 Warszawa, Poland

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Identifiers

DOI

10.12693/APhysPolA.119.84