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2014 | 61 | 2 | 385-388
Article title

Leonurus cardiaca L. herb - a derived extract and an ursolic acid as the factors affecting the adhesion capacity of Staphylococcus aureus in the context of infective endocarditis

Content
Title variants
Languages of publication
EN
Abstracts
EN
The objective was an assessment of the impact of Leonurus cardiaca L. extract (LCE) and ursolic acid (UA) on the adhesive properties of Staphylococus aureus NCTC 8325 strain, expressing virulence factors important in the pathogenesis of infective endocarditis. The adhesion and biofilm formation of bacteria cultured in the presence of subinhibitory concentrations of LCE or UA on the abiotic surface or covered with fibrinogen, fibronectin or collagen, were evaluated. Inhibitory effects of LCE and UA on staphylococcal adherence to both types of surface were demonstrated. This, in the case of UA, resulted in a significant reduction of biofilm formation.
Publisher

Year
Volume
61
Issue
2
Pages
385-388
Physical description
Dates
published
2014
received
2013-10-28
revised
2014-03-11
accepted
2014-03-27
(unknown)
2014-06-11
Contributors
  • Department of Immunology and Infectious Biology, Institute of Microbiology, Biotechnology and Immunology, University of Lodz, Łódź, Poland
  • Department of Immunology and Infectious Biology, Institute of Microbiology, Biotechnology and Immunology, University of Lodz, Łódź, Poland
  • Institute of Technical Biochemistry, Department of Biotechnology and Food Sciences Lodz Technical University, Poland, Łódź, Poland
  • Institute of Technical Biochemistry, Department of Biotechnology and Food Sciences Lodz Technical University, Poland, Łódź, Poland
  • Department of Immunology and Infectious Biology, Institute of Microbiology, Biotechnology and Immunology, University of Lodz, Łódź, Poland
References
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv61p385kz
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