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Journal
2009 | 4 | 3 | 331-336
Article title

How safe is the use of prosthetic materials in the repair of abdominal-wall defects in malnourished subjects?

Content
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Languages of publication
EN
Abstracts
EN
Incisional hernias and abdominal-wall defects consume large amounts of healthcare resources. Use of mesh is effective in treatment of these disorders and can decrease the rate of recurrence. This experimental study focused on the safety of mesh use in the setting of malnutrition, a condition that impairs wound healing. Rats were divided into two groups: normally fed and food-restricted. An abdominal-wall defect, 2 by 2 cm, was covered with polypropylene mesh, 2.5 by 2.5 cm. After sacrifice of the rats at the 21st and 60th days, tissue samples were sent for tensiometric and histopathological studies. No significant difference in infectious complications was observed between the two groups. Tensiometry revealed no significant differences between the groups. On histopathological examination, the only difference noted was in the vascularization scores of normally fed rats. For malnourished subjects that survived after surgery, the use of polypropylene mesh appeared safe in the closure of abdominal-wall defects, with no increase in infection rate and satisfactory wound healing.
Publisher

Journal
Year
Volume
4
Issue
3
Pages
331-336
Physical description
Dates
published
1 - 9 - 2009
online
3 - 7 - 2009
Contributors
  • Deparment of Surgery, Diskapi Yildirim Beyazit Teaching and Research Hospital, 06110, Ankara, Turkey
  • Deparment of Surgery, Diskapi Yildirim Beyazit Teaching and Research Hospital, 06110, Ankara, Turkey, hakankulacoglu@hotmail.com
author
  • Deparment of Surgery, Diskapi Yildirim Beyazit Teaching and Research Hospital, 06110, Ankara, Turkey
author
  • Deparment of Surgery, Diskapi Yildirim Beyazit Teaching and Research Hospital, 06110, Ankara, Turkey
  • Grad. Dept. Biotechnology, Middle East Technical University, 06530, Ankara, Turkey
  • Deparment of Pathology, Diskapi Yildirim Beyazit Teaching and Research Hospital, 06110, Ankara, Turkey
author
  • Department of Surgery, Ankara University Faculty of Veterinary Medicine, 06110, Ankara, Turkey
author
  • Deparment of Surgery, Diskapi Yildirim Beyazit Teaching and Research Hospital, 06110, Ankara, Turkey
  • Baskent University Faculty of Biomedical Engineering, 06810, Ankara, Turkey
author
  • Department of Surgery, Ankara University Faculty of Veterinary Medicine, 06110, Ankara, Turkey
  • Dept. Chemistry, Grad. Dept. Biotechnology, Grad Dept.Biomedical Engineering, Middle East Technical University, 06530, Ankara, Turkey
References
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11536-009-0029-2
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