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Journal
2008 | 3 | 4 | 521-524
Article title

Henoch-Schönlein purpura presenting with multiplex gastrointestinal manifestations and massive nephrotic syndrome in adulthood - a case report

Content
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Languages of publication
EN
Abstracts
EN
Henoch-Schönlein purpura (HSP) is a systemic small vessel vasculitis mainly affecting children. We report a case of a 49-year-old woman with severe gastrointestinal and renal involvement of HSP. Endoscopy revealed more characteristic findings in the terminal ileum than in the gastric antrum. Histological examinations of the biopsy samples from the ileum, antrum, skin and kidney confirmed the diagnosis of HSP. Parenteral corticosteroid therapy led to a rapid improvement of the gastrointestinal symptoms, but because of the excessive proteinuria intravenous cyclophosphamide therapy had to be introduced.
Publisher

Journal
Year
Volume
3
Issue
4
Pages
521-524
Physical description
Dates
published
1 - 12 - 2008
online
22 - 10 - 2008
Contributors
  • First Department of Internal Medicine, University of Szeged, H6720, Szeged, Hungary
author
  • First Department of Internal Medicine, University of Szeged, H6720, Szeged, Hungary
  • Department of Pathology, University of Szeged, H6720, Szeged, Hungary
  • Department of Pathology, University of Szeged, H6720, Szeged, Hungary
author
  • Department of Pathology, University of Szeged, H6720, Szeged, Hungary
author
  • Department of Dermatology and Allergology, University of Szeged, H6720, Szeged, Hungary
  • First Department of Internal Medicine, University of Szeged, H6720, Szeged, Hungary
References
  • [1] Tizard E.J., Henoch-Schönlein purpura, Arch. Dis. Child., 1999, 80, 380–383 http://dx.doi.org/10.1136/adc.80.4.380[Crossref]
  • [2] McKee P.H., Calonje E., Granter S.R., Pathology of the skin with clinical correlation, Elsevier Mosby, 2005, 1, 716–718
  • [3] Chen M.J., Wang T.E., Chang W.H. Tsai S.J., Liao W.S., Endoscopic findings in a patient with Henoch-Schönlein purpura, World J. Gastroenterol., 2005, 11, 2354–2356
  • [4] Sharma A., Wanchu A., Kalra N., Singh S., Bambery P., Successful treatment of severe gastrointestinal involvement in adult-onset Henoch-Schönlein purpura, Singapore Med. J., 2007, 48, 1047–1050 [PubMed]
  • [5] Karagozian R., Turbide C., Szilagyi A., Henoch-Schonlein purpura presenting with ileal involvement in an adult, Dig. Dis. Sci., 2004, 49, 1722–1726 http://dx.doi.org/10.1023/B:DDAS.0000043392.64347.ea[Crossref]
  • [6] Rieu P., Noel L.H., Henoch-Schönlein nephritis in children and adults. Morphological features and clinicopathological correlations, Ann. Med. Intern., 1999, 150, 151–159
  • [7] Shenoy M., Bradbury M.G., Lewis M.A., Webb N.J., Outcome of Henoch-Schönlein purpura nephritis treated with long-term immunosuppression, Pediatr. Nephrol., 2007, 22, 1717–1722 http://dx.doi.org/10.1007/s00467-007-0557-4[Crossref]
  • [8] de Almeida J.L., Campos L.M.A., Paim L.B., Leone C., Koch V.H., Silva C.A., Renal involvement in Henoch-Schönlein purpura: a multivariate analysis of initial prognostic factors, J. Pediatr., 2007, 83, 259–266 http://dx.doi.org/10.2223/JPED.1638[Crossref][WoS]
  • [9] Coppo R., Andrulli S., Amore A., Gianoglio B., Conti G., Peruzzi L., et al., Predictors of outcome in Henoch-Schönlein nephritis in chlidren and adults, Am. J. Kidney Dis., 2006, 47, 993–1003 http://dx.doi.org/10.1053/j.ajkd.2006.02.178[Crossref]
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11536-008-0060-8
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