Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl

PL EN


Preferences help
enabled [disable] Abstract
Number of results

Journal

2014 | 12 | 10 | 714-718

Article title

MCNP simulation of the dose distribution in liver cancer treatment for BNC therapy

Content

Title variants

Languages of publication

EN

Abstracts

EN
The Boron Neutron Capture Therapy (BNCT) is based on selective uptake of boron in tumour tissue compared to the surrounding normal tissue. Infusion of compounds with boron is followed by irradiation with neutrons. Neutron capture on 10B, which gives rise to an alpha particle and recoiled 7Li ion, enables the therapeutic dose to be delivered to tumour tissue while healthy tissue can be spared. Here, therapeutic abilities of BNCT were studied for possible treatment of liver cancer using thermal and epithermal neutron beam. For neutron transport MCNP software was used and doses in organs of interest in ORNL phantom were evaluated. Phantom organs were filled with voxels in order to obtain depth-dose distributions in them. The result suggests that BNCT using an epithermal neutron beam could be applied for liver cancer treatment.

Publisher

Journal

Year

Volume

12

Issue

10

Pages

714-718

Physical description

Dates

published
1 - 10 - 2014
online
16 - 8 - 2014

Contributors

  • Faculty of Science, University of Kragujevac, R. Domanovica 12, 34000, Kragujevac, Serbia
  • Faculty of Science, University of Kragujevac, R. Domanovica 12, 34000, Kragujevac, Serbia
  • Faculty of Science, University of Kragujevac, R. Domanovica 12, 34000, Kragujevac, Serbia
  • Faculty of Science, University of Kragujevac, R. Domanovica 12, 34000, Kragujevac, Serbia
  • Faculty of Technical Science, University of Kragujevac, Svetog Save 65, 32000, Cacak, Serbia

References

  • [1] D. L. Bleuel, W. T. Chu, R. J. Donahue, B. A. Ludewigta, J. Vujic, Med. Phys. 25, 1725 (1998) http://dx.doi.org/10.1118/1.598353[Crossref]
  • [2] F. El Moussaoui, T. El Bardouni, M. Azahra, A. Kamili, H. Boukhal, Cancer/Radiotherapie 12, 360 (2008) http://dx.doi.org/10.1016/j.canrad.2008.03.005[Crossref]
  • [3] A. Zonta et al., Appl. Radiat. Isot. 67, S67 (2009) http://dx.doi.org/10.1016/j.apradiso.2009.03.087[Crossref]
  • [4] G. Gambarini, G. G. Daquino, R. L. Moss, M. Carrara, V. A. Nievaart, E. Vanossi, Radiat. Prot. Dosim. 126, 604 (2007) http://dx.doi.org/10.1093/rpd/ncm123[Crossref]
  • [5] T. Pinelli et al., Eighth International Symposium, 1998, Los Angeles, CA, USA (Kluwer Academic/Plenum Publishers, New York, 2001) 1427
  • [6] A. Zonta et al., J. Phys.: Conference Series 41, 484 (2006) http://dx.doi.org/10.1088/1742-6596/41/1/054[Crossref]
  • [7] S. Bortolussi et al., Appl. Radiat. Isot. 69, 1924 (2011) http://dx.doi.org/10.1016/j.apradiso.2011.03.034[Crossref]
  • [8] L. Kankaanranta et al., Int. J. Radiation Oncol. Biol. Phys. 69, 475 (2007) http://dx.doi.org/10.1016/j.ijrobp.2007.03.039[Crossref]
  • [9] I. Porras, Phys. Med. Biol. 57, L1 (2008) http://dx.doi.org/10.1088/0031-9155/53/7/L01[Crossref]
  • [10] I. Porras, Appl. Radiat. Isot. 69, 1838 (2011) http://dx.doi.org/10.1016/j.apradiso.2011.04.002[Crossref]
  • [11] H. Horiguchi, T. Nakamura, H. Kumada, H. Yanagie, M. Suzuki, H. Sagawa, Appl. Radiat. Isot. 69, 1882 (2011) http://dx.doi.org/10.1016/j.apradiso.2011.03.036[Crossref]
  • [12] D. Krstic, V. M. Markovic, Z. Jovanovic, B. Milenkovic, D. Nikezic, J. Atanackovic, Radiat. Prot. Dosim. DOI:10.1093/rpd/nct365. [Crossref]
  • [13] K. F. Eckerman, M. Cristy, J. C. Ryman The ORNL Mathematical Phantom Series, Oak Ridge National Laboratory Report, (Oak Ridge, TN, USA, 1996) Updated 08 April (2009)
  • [14] D. Krstic, D. Nikezic, Comp. Phys. Commun. 176, 33 (2007) http://dx.doi.org/10.1016/j.cpc.2006.06.016[Crossref]
  • [15] X-5 Monte Carlo Team, MCNP’a General Monte Carlo N-Particle Transport Code, Version 5 Vol. I: Overview and Theory (Los Alamos National Laboratory, Los Alamos, 2003)
  • [16] T. Matsumoto, Nucl. Instrum. Meth. A 580, 552 (2007) http://dx.doi.org/10.1016/j.nima.2007.05.233[Crossref]

Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11534-014-0507-2
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.