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Journal
2014 | 12 | 10 | 714-718
Article title

MCNP simulation of the dose distribution in liver cancer treatment for BNC therapy

Content
Title variants
Languages of publication
EN
Abstracts
EN
The Boron Neutron Capture Therapy (BNCT) is based on selective uptake of boron in tumour tissue compared to the surrounding normal tissue. Infusion of compounds with boron is followed by irradiation with neutrons. Neutron capture on 10B, which gives rise to an alpha particle and recoiled 7Li ion, enables the therapeutic dose to be delivered to tumour tissue while healthy tissue can be spared. Here, therapeutic abilities of BNCT were studied for possible treatment of liver cancer using thermal and epithermal neutron beam. For neutron transport MCNP software was used and doses in organs of interest in ORNL phantom were evaluated. Phantom organs were filled with voxels in order to obtain depth-dose distributions in them. The result suggests that BNCT using an epithermal neutron beam could be applied for liver cancer treatment.
Publisher
Journal
Year
Volume
12
Issue
10
Pages
714-718
Physical description
Dates
published
1 - 10 - 2014
online
16 - 8 - 2014
References
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Document Type
Publication order reference
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11534-014-0507-2
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