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2014 | 12 | 8 | 858-867

Article title

Polyphenols in Coreopsis tinctoria Nutt. fruits and the plant extracts antioxidant capacity evaluation


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The aim of this research was to investigate the chemical composition of Coreopsis tinctoria Nutt. fruits extract, to highlight the potential of ultrasound assisted extraction in the fast preparation of extracts rich in polyphenols using different solvents (55%, 78% and 96% hydrous ethanol) and to evaluate the antioxidant potential of formulated extracts. LC-MS/MS was used to characterize the ethanolic extract from Coreopsis tinctoria Nutt. dried fruits. The extract contains different flavonoids (marein, flavanomarein, quercetagetin-7-O-glucoside, okanin aurone, leptosidin, luteolin, apigenin) and phenolic acids (chlorogenic acid, caffeic acid). Several parameters that could affect extraction efficiency were evaluated. Finally, this study focused on determination of plant extracts total phenolic content and their antioxidant capacity. The experimental results allowed the selection of the optimum operating parameters leading to the highest total polyphenolic content, expressed as gallic acid equivalents, and avoiding the degradation of phenolic compounds (ethanol 55%; extraction temperature 323.15 K, extraction time 30 min, liquid/solid ratio 20/1). A good relationship between total phenolic content and antioxidant capacity was obtained.










Physical description


1 - 8 - 2014
1 - 5 - 2014


  • University of Bucharest
  • University POLITEHNICA of Bucharest
  • University POLITEHNICA of Bucharest
  • University of Bucharest
  • Cytogenomic Medical Laboratory
  • National Institute of Research and Development for Biological Sciences
  • National Institute of Research and Development for Biological Sciences
  • National Institute of Research and Development for Biological Sciences
  • University of Medicine and Pharmaceutics “Carol Davila”
  • University of Medicine and Pharmaceutics “Carol Davila”


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