Polyphenols in Coreopsis tinctoria Nutt. fruits and the plant extracts antioxidant capacity evaluation

• Authors: Christina Zălaru , Claudia Crişan , Ioan Călinescu , Zenovia Moldovan , Isabela Ţârcomnicu , Simona Litescu , Rodica Tatia , Lucia Moldovan , Daniel Boda , Mircea Iovu
• Languages of publication: EN

Abstracts

EN

The aim of this research was to investigate the chemical composition of Coreopsis tinctoria Nutt. fruits extract, to highlight the potential of ultrasound assisted extraction in the fast preparation of extracts rich in polyphenols using different solvents (55%, 78% and 96% hydrous ethanol) and to evaluate the antioxidant potential of formulated extracts. LC-MS/MS was used to characterize the ethanolic extract from Coreopsis tinctoria Nutt. dried fruits. The extract contains different flavonoids (marein, flavanomarein, quercetagetin-7-O-glucoside, okanin aurone, leptosidin, luteolin, apigenin) and phenolic acids (chlorogenic acid, caffeic acid). Several parameters that could affect extraction efficiency were evaluated. Finally, this study focused on determination of plant extracts total phenolic content and their antioxidant capacity. The experimental results allowed the selection of the optimum operating parameters leading to the highest total polyphenolic content, expressed as gallic acid equivalents, and avoiding the degradation of phenolic compounds (ethanol 55%; extraction temperature 323.15 K, extraction time 30 min, liquid/solid ratio 20/1). A good relationship between total phenolic content and antioxidant capacity was obtained.

Keywords

EN

Coreopsis tinctoria Nutt. fruits; Polyphenols; Ultrasound assisted extraction; Antioxidant capacity

• Publisher: De Gruyter Open
• Journal: Open Chemistry
• Year: 2014
• Volume: 12
• Issue: 8
• Pages: 858-867

Dates

published

1 - 8 - 2014

online

1 - 5 - 2014

Contributors

author

Christina Zălaru

• University of Bucharest

author

Claudia Crişan

• University POLITEHNICA of Bucharest

author

Ioan Călinescu

• University POLITEHNICA of Bucharest

author

Zenovia Moldovan

• University of Bucharest

author

Isabela Ţârcomnicu

• Cytogenomic Medical Laboratory

author

Simona Litescu

• National Institute of Research and Development for Biological Sciences

author

Rodica Tatia

• National Institute of Research and Development for Biological Sciences

author

Lucia Moldovan

• National Institute of Research and Development for Biological Sciences

author

Daniel Boda

• University of Medicine and Pharmaceutics “Carol Davila”

author

Mircea Iovu

• University of Medicine and Pharmaceutics “Carol Davila”

References

• [1] T. Săvulescu, E.I. Nyárády, E. Ghişa, I. Grinţescu, M. Guşuleac, I. Morariu, I. Prodan, Flora Republicii Populare Romîne (Editura Academiei Republicii Populare Romîne, Romania, 1964) vol. IX (in Romanian)
• [2] C. Chirilă, J. Marin, E. Calmuş, Plante tinctoriale şi folosirea lor pentru vopsitul lânii (Curtea Veche Trading, Bucureşti, 1999) (in Romanian)
• [3] S. Foster, J.A. Duke, A field guide to medicinal plants. Eastern and Central North America (Houghton Mifflin Co., Boston, 1990)
• [4] T. Dias, M.R. Bronze, P.J. Houghton, H. Mota-Filipe, A. Paulo, J. Ethnopharmacol. 132, 483 (2010) http://dx.doi.org/10.1016/j.jep.2010.08.048[Crossref]
• [5] T.A. Geissman, C.D. Heaton, J. Am. Chem. Soc. 65(4), 677 (1943) http://dx.doi.org/10.1021/ja01244a050[Crossref]
• [6] T.A. Geissman, C.D. Heaton, J. Am. Chem. Soc. 66(3), 486 (1944) http://dx.doi.org/10.1021/ja01231a056[Crossref]
• [7] T.A. Geissman, J.B. Harborne, M.K. Seikel, J. Am. Chem. Soc. 78(4), 825 (1956) http://dx.doi.org/10.1021/ja01585a032[Crossref]
• [8] J.B. Harborne, T.A. Geissman, J. Am. Chem. Soc. 78(4), 829 (1956) http://dx.doi.org/10.1021/ja01585a033[Crossref]
• [9] M. Shimokoriyama, S. Hattori, J. Am. Chem. Soc. 75, 1900 (1953) http://dx.doi.org/10.1021/ja01104a036[Crossref]
• [10] M. Shimokoriyama, J. Am. Chem. Soc. 79, 214 (1957) http://dx.doi.org/10.1021/ja01558a057[Crossref]
• [11] K. W. Nicholls, B.A. Bohm, Phytochemistry 18, 1076 (1979) http://dx.doi.org/10.1016/S0031-9422(00)91489-4[Crossref]
• [12] Y. Zhang, S. Shi, M. Zhao, Y. Jiang, P. Tu, Biochem. Syst. Ecol. 34, 766 (2006) http://dx.doi.org/10.1016/j.bse.2006.05.005[Crossref]
• [13] T. Dias, B. Liu, P. Jones, P.J. Houghton, H. Mota-Filipe, A. Paulo, J. Ethnopharmacol. doi:10.1016/j.jep.2011.11.038 (2011) [Crossref]
• [14] L. Gaspar, A.P. Oliveira, L.R. Silva, P.B. Andrade, P. Guedes de Pinho, J. Botelho, P. Valentão, Rev. Bras. Farmacogn. 22(2), 350 (2011) http://dx.doi.org/10.1590/S0102-695X2011005000224[Crossref]
• [15] C.C. Crişan, I. Călinescu, Ch. Zălaru, Z. Moldovan, U.P.B. Sci. Bull. 75(4), 169 (2013)
• [16] V. Bojňanský, A. Fargašová, Atlas of Seeds and Fruits of Central and East-European Flora The Carpathian Mountains Region (Springer, Dordrecht, The Netherlands, 2007) 677
• [17] ISO 14502-1: 2005. Determination of substances characteristic of green and black tea. Part 1: Content of total polyphenols in tea - Colorimetric method using Folin-Ciocalteu reagent.
• [18] P.C. Eklund, O.K. Langvik. J.P. Warna, T.O. Salmi, S.M. Willfor, R.E. Sjoholm, Org. Biomol. Chem. 7, 2367 (2009) http://dx.doi.org/10.1039/b822661j[Crossref]
• [19] R. Govindarajan, S. Rastogi, M. Vijayakumar, A. Shirwaikar, A.K.S. Rawat, S. Methrotra, P. Pushpangadan, Biol. Pharm. Bull. 26, 1424 (2003) http://dx.doi.org/10.1248/bpb.26.1424[Crossref]
• [20] R. van den Berg, G.R.M.M. Haenen, H. van den Berg, A. Bast, Food Chem. 70(3), 391 (2000) http://dx.doi.org/10.1016/S0308-8146(00)00092-3[Crossref]
• [21] R. Re, N. Pellegrini, A. Proteggente, A. Pannala, M. Yang, C. Rice-Evans, Free Radical Bio. Med. 26, 1231 (1999) http://dx.doi.org/10.1016/S0891-5849(98)00315-3[Crossref]
• [22] V. Exarchou, N. Nenadis, M. Tsimidou, I.P. Gerothanassis, A. Troganis, D. Boskou, J. Agr. Food Chem. 50(19), 5294 (2002) http://dx.doi.org/10.1021/jf020408a[Crossref]
• [23] F. Ferreres, D.M. Pererra, P. Valentao, P.B. Andrade, R.M. Seabra, M. Sottomayor, J. Agr. Food Chem. 56(21), 9967 (2008) http://dx.doi.org/10.1021/jf8022723[Crossref]
• [24] R. Apak, S. Gorinstein, V. Böhm, K.M. Schaich, M. Özyürek, K. Güçlü, Pure Appl. Chem. 85(5), 957 (2013) http://dx.doi.org/10.1351/PAC-REP-12-07-15[Crossref]
• [25] A.O. Danila, F. Gatea, G.L. Radu, Chem. Nat. Compd. 47(1), 22 (2011) http://dx.doi.org/10.1007/s10600-011-9822-7[Crossref]

Identifiers

DOI

10.2478/s11532-014-0539-x