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Journal
2013 | 11 | 7 | 1150-1162
Article title

Five different columns in the analysis of basic drugs in hydrophilic interaction liquid chromatography

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EN
Abstracts
EN
Five different columns (two silica, two cyanopropyl and one diol) were investigated in hydrophilic interaction liquid chromatography (HILIC). For the assessment of columns behavior in HILIC mode, six basic drugs (lamotrigine, thioridazine, clozapine, chlorpheniramine, pheniramine and sulpiride) were chosen. The assessment of the influence of the concentration of organic modifier on analytes’ retention on each column was provided by fitting the retention data into theoretical models. Utilizing the statistical analysis, the selection of the model that provides better prediction of the retention behavior was enabled. Dual RP-HILIC mechanism was suggested on cyanopropyl and diol columns, therefore the transition points between the two mechanisms on these columns were calculated. Furthermore, in order to investigate the impact of three factors simultaneously on the retention behavior of the analyzed substances on Betasil Silica column, chemometrically-aided empirical models were built. The experiments were conducted according to the matrix of Box-Behnken design and on the basis of the retention data, six quadratic models were obtained and their adequacy was confirmed using ANOVA test. The obtained coefficients of quadratic models enabled the elucidation of both single factor and factor interactions influence. This was also graphically presented in 3D response surface plots. [...]
Publisher
Journal
Year
Volume
11
Issue
7
Pages
1150-1162
Physical description
Dates
published
1 - 7 - 2013
online
26 - 4 - 2013
References
  • [1] J.C. Linden, C.L. Lawhead, J. Chromatogr. 105, 125 (1975) http://dx.doi.org/10.1016/S0021-9673(01)81096-7[Crossref]
  • [2] J.K. Palmer, Anal. Lett. 8, 215 (1975) http://dx.doi.org/10.1080/00032717508058200[Crossref]
  • [3] P. Hemstrom, K. Irgum, J. Sep. Sci. 29, 1784 (2006) http://dx.doi.org/10.1002/jssc.200600199[Crossref]
  • [4] P. Jandera, Anal. Chim. Acta 692, 1 (2011) http://dx.doi.org/10.1016/j.aca.2011.02.047[Crossref]
  • [5] A.J. Alpert, J. Chromatogr. 499, 177 (1990) http://dx.doi.org/10.1016/S0021-9673(00)96972-3[Crossref]
  • [6] B. Dejaegher, Y. Vander Heyden, J. Sep. Sci. 33, 698 (2010) http://dx.doi.org/10.1002/jssc.200900742[Crossref]
  • [7] T. Yoshida, J. Biochem. Biophys. Methods 60, 265 (2004) http://dx.doi.org/10.1016/j.jbbm.2004.01.006[Crossref]
  • [8] B.A. Olsen, J. Chromatogr. A 913, 113 (2001) http://dx.doi.org/10.1016/S0021-9673(00)01063-3[Crossref]
  • [9] D.V. McCalley, U.D. Neue, J. Chromatogr. A 1192, 225 (2008) http://dx.doi.org/10.1016/j.chroma.2008.03.049[Crossref]
  • [10] D.V. McCalley, J. Chromatogr. A 1217, 3408 (2010) http://dx.doi.org/10.1016/j.chroma.2010.03.011[Crossref]
  • [11] A.E. Karatapanis, Y.C. Fiamegos, C.D. Stalikas, Chromatographia 71, 751 (2010) http://dx.doi.org/10.1365/s10337-010-1564-3[Crossref]
  • [12] N.S. Quiming, N.L. Denola, Y. Saito, A.P. Catabay, K. Jinno, Chromatographia 67, 507 (2008) http://dx.doi.org/10.1365/s10337-008-0559-9[Crossref]
  • [13] R. Li, Y. Zhang, C.C. Lee, L. Liu, Y. Huang, J. Sep. Sci. 34, 1508 (2011) http://dx.doi.org/10.1002/jssc.201100130[Crossref]
  • [14] T. Yoshida, Anal. Chem. 69, 3038 (1997) http://dx.doi.org/10.1021/ac9702204[Crossref]
  • [15] N.F. Al-Tannak, S. Bawazeer, T.H. Siddiqui, D.G. Watson, J. Chromatogr. A 1218, 1486 (2011) http://dx.doi.org/10.1016/j.chroma.2011.01.036[Crossref]
  • [16] R.-I. Chirita, C. West, S. Zubrzycki, A.-L. Finaru, C. Elfakir, J. Chromatogr. A 1218, 5939 (2011) http://dx.doi.org/10.1016/j.chroma.2011.04.002[Crossref]
  • [17] T. Ikegami, K. Tomomatsu, H. Takubo, K. Horie, N. Tanaka, J. Chromatogr. A 1184, 474 (2008) http://dx.doi.org/10.1016/j.chroma.2008.01.075[Crossref]
  • [18] A.E. Karatapanis, Y.C. Fiamegos, C.D. Stalikas, J. Chromatogr. A 1218, 2871 (2011) http://dx.doi.org/10.1016/j.chroma.2011.02.069[Crossref]
  • [19] E. Bourgogne, F.-X. Mathy, D. Boucaut, H. Boekens, O. Laprevote, Anal. Bioanal. Chem. 402, 449 (2012) http://dx.doi.org/10.1007/s00216-011-5224-8[Crossref]
  • [20] I.B. Paek, Y. Moon, H. Y. Ji, H.-H. Kim, H.W. Lee, Y.-B. Lee, H.S. Lee, J. Chromatogr. B 809, 345 (2004)
  • [21] A. D’Attoma, C. Grivel, S Heinisch, J. Chromatogr. A 1262, 148 (2012) http://dx.doi.org/10.1016/j.chroma.2012.09.028[Crossref]
  • [22] N. El-Enany, D. El-Sherbiny, A. Abdelal, F. Belal, J. Liq. Chromatogr. 35, 819 (2012) [Crossref]
  • [23] E. Rozet, P. Lebrun, B. Debrus, B. Boulanger, P. Hubert, Trends in Analytical Chemistry 42, 157 (2013) http://dx.doi.org/10.1016/j.trac.2012.09.007[Crossref]
  • [24] R. Cela, E.Y. Ordonez, J.B. Quintana, R. Rodil, J. Chromatogr. A, article in press (2012)
  • [25] J.R. Torres-Lapasi, M.C. Garcia-Alvarez-Coque, E. Bosch, M. Rosés, J. Chromatogr. A 1089, 170 (2005) http://dx.doi.org/10.1016/j.chroma.2005.06.085[Crossref]
  • [26] L.R. Snyder, J.W. Dolan, J.R. Grant, J. Chromatogr. 165, 3 (1979) http://dx.doi.org/10.1016/S0021-9673(00)85726-X[Crossref]
  • [27] P. Jandera, J. Churaček, L. Svoboda, J. Chromatogr. 174, 35 (1979) http://dx.doi.org/10.1016/S0021-9673(00)87035-1[Crossref]
  • [28] L.R. Snyder, Anal. Chem. 46, 1384 (1974) http://dx.doi.org/10.1021/ac60347a052[Crossref]
  • [29] P. Jandera, T. Hajek, J. Sep. Sci. 32, 3603 (2009) http://dx.doi.org/10.1002/jssc.200900344[Crossref]
  • [30] G. Jin, Z. Guo, F. Zhang, X. Xue, Y. Jin, X. Liang, Talanta 76, 522 (2008) http://dx.doi.org/10.1016/j.talanta.2008.03.042[Crossref]
  • [31] S.N. Deming, S.L. Morgan, Experimental design: a chemometric approach, 2nd edition (Elsevier Science Publishers B. V, Amsterdam, 1993)
  • [32] W.O. Foye, T.L. Lemke, D.A. Williams, Principles of Medicinal Chemistry, 4th edition (Williams & Williams, Boston, 1995)
  • [33] Y. Guo, S. Gaiki, J. Chromatogr. A 1218, 5920 (2011) http://dx.doi.org/10.1016/j.chroma.2011.06.052[Crossref]
  • [34] S.L.C. Ferreira, R.E. Bruns, E.G.P. da Silva, W.N.L. dos Santos, C.M. Quintella, J.M. Davis, J.B. de Andrade, M.C. Breitkreitz, I.C.S.F. Jardim, B.B. Neto, J. Chromatogr. A 1158, 2 (2007) http://dx.doi.org/10.1016/j.chroma.2007.03.051[Crossref]
  • [35] R.L. Mason, R.F. Gunst, J.L. Hess, Statistical Design and Analysis of Experiments With Aplication to Engineering and Science, 2nd edition (Hoboken, New Jersey, 2003) http://dx.doi.org/10.1002/0471458503[Crossref]
Document Type
Publication order reference
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11532-013-0245-0
Identifiers
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