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Number of results

Journal

2010 | 8 | 5 | 1078-1085

Article title

Conductometric studies on the stability of copper complexes with different oligosaccharides

Content

Title variants

Languages of publication

EN

Abstracts

EN
Bioactive copper complexes with pullulan or dextran oligosaccharides are the subject of intensive research mainly because of their possible application in veterinary and human medicine. The thermal stability and stability under oxidative conditions of the Cu(II) complexes with reduced low-molar pullulan or dextran were investigated in this paper, using a conductometric method. The influence of ligand constitutions on the stability of the complexes was examined on the basis of ligand property. Forced degradation studies were performed on bulk sample of complexes by using heat (25, 40 and 60°C) and an oxidation agent (0.1, 0.5, 1.0 and 10.0% v/v hydrogen peroxide). It can be concluded, according to the results obtained (by examining conductivity during the forced degradation studies), that Cu(II) complexes show a large pharmaceutical stability for both tests. [...]

Publisher

Journal

Year

Volume

8

Issue

5

Pages

1078-1085

Physical description

Dates

published
1 - 10 - 2010
online
5 - 9 - 2010

Contributors

author
  • Department of Pharmaceutics, Faculty of Technology, University of Nis, Leskovac, 16000, Serbia
author
  • Department of Pharmaceutics, Faculty of Technology, University of Nis, Leskovac, 16000, Serbia
author
  • Department of Pharmaceutics, Faculty of Technology, University of Nis, Leskovac, 16000, Serbia
author
  • Department of Pharmaceutics, Faculty of Technology, University of Nis, Leskovac, 16000, Serbia

References

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Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11532-010-0082-3
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