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2010 | 8 | 5 | 1078-1085
Article title

Conductometric studies on the stability of copper complexes with different oligosaccharides

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EN
Abstracts
EN
Bioactive copper complexes with pullulan or dextran oligosaccharides are the subject of intensive research mainly because of their possible application in veterinary and human medicine. The thermal stability and stability under oxidative conditions of the Cu(II) complexes with reduced low-molar pullulan or dextran were investigated in this paper, using a conductometric method. The influence of ligand constitutions on the stability of the complexes was examined on the basis of ligand property. Forced degradation studies were performed on bulk sample of complexes by using heat (25, 40 and 60°C) and an oxidation agent (0.1, 0.5, 1.0 and 10.0% v/v hydrogen peroxide). It can be concluded, according to the results obtained (by examining conductivity during the forced degradation studies), that Cu(II) complexes show a large pharmaceutical stability for both tests. [...]
Publisher
Journal
Year
Volume
8
Issue
5
Pages
1078-1085
Physical description
Dates
published
1 - 10 - 2010
online
5 - 9 - 2010
References
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Document Type
Publication order reference
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11532-010-0082-3
Identifiers
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