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Journal
2010 | 8 | 2 | 273-277
Article title

A fast determination of yohimbine in pharmaceuticals by micellar electrokinetic chromatography

Content
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EN
Abstracts
EN
A method for the fast determination of yohimbine, a potent adrenoreceptor antagonist used for the treatment of sexual dysfunctions, is proposed in this article. MEKC under basic and acidic conditions (sodium borate, pH 9.5 and sodium phosphate, pH 2.5) with SDS was developed. The effect of the experimental parameters, e.g. pH, SDS concentration and injection time, on yohimbine migration was also studied. Both methods were validated in terms of linearity, limits of detection and quantification, accuracy, and precision using caffeine as an internal standard. The application for the determination of yohimbine in hand-made medicaments is also investigated in this study. [...]
Publisher

Journal
Year
Volume
8
Issue
2
Pages
273-277
Physical description
Dates
published
1 - 4 - 2010
online
23 - 3 - 2010
Contributors
  • Department of Analytical Chemistry, Faculty of Science, Palacký University in Olomouc, CZ-77146, Olomouc, Czech Republic
  • Department of Clinical Biochemistry, University Hospital Olomouc, CZ-77520, Olomouc, Czech Republic
  • Department of Analytical Chemistry, Faculty of Science, Palacký University in Olomouc, CZ-77146, Olomouc, Czech Republic
author
  • Department of Analytical Chemistry, Faculty of Science, Palacký University in Olomouc, CZ-77146, Olomouc, Czech Republic
  • Department of Analytical Chemistry, Faculty of Science, Palacký University in Olomouc, CZ-77146, Olomouc, Czech Republic
  • Department of Analytical Chemistry, Faculty of Science, Palacký University in Olomouc, CZ-77146, Olomouc, Czech Republic
References
  • [1] S.W. Tam, M. Worcel, M. Wyllie, Pharmacol Therap. 91, 215 (2001) http://dx.doi.org/10.1016/S0163-7258(01)00156-5[Crossref]
  • [2] A.J. Riley, Brit. J. Clin. Practic. 48, 133 (1994)
  • [3] K. Valentová, P. Entnerová, J. Urbaníková, V. Šimánek, Chem. Listy 98, 1119 (2004)
  • [4] P. Le Corre, G. Dollo, F. Chevanne, R. Le Verge, Eur. J. Pharm. Sci. 9, 79 (1999) http://dx.doi.org/10.1016/S0928-0987(99)00046-9[Crossref]
  • [5] B. Diquet, L. Doare, G. Gaudel, J. Chromatogr. 311, 449 (1984) http://dx.doi.org/10.1016/S0378-4347(00)84745-3[Crossref]
  • [6] R. Chiba, Y. Ishii, J. Chromatogr. 588, 344 (1991) http://dx.doi.org/10.1016/0021-9673(91)85044-G[Crossref]
  • [7] R. Le Verge, P. Le Corre, F. Chevanne, M.D. De Maindreville, D. Royer, J. Levy, J. Chromatogr. 574, 283 (1992) http://dx.doi.org/10.1016/0378-4347(92)80041-N[Crossref]
  • [8] T. K. Natishan, J. Liq. Chromatogr. RT 28, 1115 (2005) http://dx.doi.org/10.1081/JLC-200053014[Crossref]
  • [9] P.T.T. Ha, J. Hoogmartens, A. Van Schepdael, J. Pharm. Biomed. Anal. 41, 1 (2006) http://dx.doi.org/10.1016/j.jpba.2006.01.035[Crossref]
  • [10] J. Zhang, J. Konečný, Z. Glatz, J. Hoogmartens, A. Van Schepdael, Curr. Anal. Chem. 3, 197 (2007) http://dx.doi.org/10.2174/157341107781023794[Crossref]
  • [11] A. Jouyban, E. Kenndler, Electrophoresis 29, 3531 (2008) http://dx.doi.org/10.1002/elps.200800054[Crossref]
  • [12] S. Terabe, K. Otsuka, K. Ichikawa, A. Tsuchiya, T. Ando, Anal. Chem. 56, 111 (1984). http://dx.doi.org/10.1021/ac00265a031[Crossref]
  • [13] D.E. Burton, M.J. Sepaniak, M.P. Maskarinec, J. Chromatogr. Sci. 24, 347 (1986). [Crossref]
  • [14] S. Terabe, Chem. Rec. 8, 291 (2008) http://dx.doi.org/10.1002/tcr.20156[Crossref]
  • [15] M. Silva, Electrophoresis 30, 50 (2009) http://dx.doi.org/10.1002/elps.200800414[Crossref]
  • [16] Q. Chen, P. Li, Z. Zhang, K. Li, J. Liu, Q. Li, J. Sep. Sci. 31, 2211 (2008) http://dx.doi.org/10.1002/jssc.200800055[Crossref]
  • [17] J.W. Cooper, P.A. Craig, FASEB J. 14, A1470 (2000)
  • [18] H. Wätzig, M. Degenhardt, A. Kunkel, Electrophoresis 19, 2695 (1998) http://dx.doi.org/10.1002/elps.1150191603[Crossref]
  • [19] M.L. Riekkola, S.K. Wiedmer, I.E. Valko, H. Siren, J. Chromatogr. A 792, 13 (1997) http://dx.doi.org/10.1016/S0021-9673(97)00728-0[Crossref]
  • [20] J.S. Fritz, Electrophoresis 24, 1530 (2003) http://dx.doi.org/10.1002/elps.200305397[Crossref]
  • [21] E. Kenndler, Electrophoresis 30, S101 (2009) http://dx.doi.org/10.1002/elps.200900180[Crossref]
  • [22] Z. Malá, A. Šlampová, P. Gebauer, P. Boček, Electrophoresis 30, 215 (2009) http://dx.doi.org/10.1002/elps.200800433[Crossref]
  • [23] M.C. Breadmore, J.R.E. Thabano, M. Dawod, A.A. Kazarian, J.P. Quirino, R.M. Guijt, Electrophoresis 30, 230 (2009) http://dx.doi.org/10.1002/elps.200800435[Crossref]
  • [24] P. Gebauer, P. Boček, Electrophoresis 30, S27 (2009) http://dx.doi.org/10.1002/elps.200900053[Crossref]
  • [25] J.P. Quirino, S. Terabe, J. Chromatogr. A 781, 119 (1997) http://dx.doi.org/10.1016/S0021-9673(97)00498-6[Crossref]
  • [26] S.L. Simpson, J.P. Quirino, S. Terabe, J. Chromatogr. A 1184, 504 (2008) http://dx.doi.org/10.1016/j.chroma.2007.11.001[Crossref]
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11532-009-0149-1
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