PSJD - Yadda

1

Risk Factors for Wound Dehiscence after Laparotomy – Clinical Control Trial

100%

Kenig J., Richter P., Żurawska S., Lasek A., Zbierska K., Nowak W.

Polish Journal of Surgery

|

2012

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vol. 84

|

issue 11

565-573

EN

Described in the literature dehiscence rate in the adult population is 0.3-3.5%, and in the elderly group as much as 10%. In about 20-45% evisceration becomes a significant risk factor of death in the perioperative period. The aim of the study was to identify the main risk factors for abdominal wound dehiscence in the adult population. Material and methods. The study included patients treated in the 3rd Department of General Surgery, Jagiellonian University Collegium Medicum in Cracow in the period from January 2008 to December 2011, in which at that time laparotomy was performed and was complicated by wound dehiscence in the postoperative period. For each person in a research group, 3-4 control patient were selected. Selection criteria were corresponding age (± 2-3 years), gender, underlying disease and type of surgery performed. Results. In 56 patients (2.9%) dehiscence occurred in the postoperative period with 25% mortality. The group consisted of 37 men and 19 women with the mean age of 66.8 ± 12.6 years. Univariate analysis showed that chronic steroids use, surgical site infection, anastomotic dehiscence/fistula in the postoperative period and damage to the gastrointestinal tract are statistically significant risk factors for dehiscence. Two first of these factors occurred to be independent risk factors in the multivariate analysis. In addition, due to the selection criteria, a group of risk factors should also include male gender, emergency operation, midline laparotomy, colorectal syrgery and elderly age (> 65 years). Logistic regression analysis did not show that a particular surgeon, time of surgery or a particular month (including holiday months) were statistically significant risk factor for dehiscence. Conclusions. Wound dehiscence is a serious complication with relatively small incidence but also high mortality. Preoperative identification of risk factors allows for a more informed consent before patient’s treatment and to take measures to prevent or minimize the consequences of complication associated with it.

2

Follow-up on the diagnostic level of children covered by the Universal Neonatal Hearing Screening Program in Poland, divided into voivodships

80%

Greczka G., Zych M., Dąbrowski P., Gasińska A., Król A., Szyfter-Harris J., Szyfter W.

Polish Journal of Otolaryngology

|

2019

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vol. 73

|

issue 4

1-7

EN

Introduction: Thanks to the Polish Universal Neonatal Hearing Screening Program (PUNHSP), all newborns in Poland undergo a free, screening hearing examination. Between 2006 and 2015, the average number of tested children per year was 373,477. According to the analysis of The Central Database (CDB), only 55.8% of the children attended the detailed hearing examinations at the second level of the Program. Aim: The aim of this study is to analyse the dates concerning the attendance of the children at the diagnostic level of PUNHSP in different regions of Poland. Materials and methods: To conduct an analysis of this fact and find out the reasons for low attendance at the second level in 2015, a telephone survey questionnaire was developed for parents who had not registered their babies for further consultation – 3,239 randomly selected parents. Results: The analysis revealed that the number of children examined at the second diagnostic level of the program is in fact much higher than the results of The Central Database show. The actual number is 83.6% as opposed to 55.8%. As a result of the telephone questionnaire some inaccuracies in the input data to the CDB were detected. The main errors in gathering the information for the CDB were incorrect OAE test result and no examination performed. C onclusion: In Poland the worst results (i.e. questionnaire results compared to CDB) for the attendance at the diagnostic level were shown in Pomorskie, Lubelskie, Mazowieckie and Podlaskie regions. In many cases there was a large discrepancy between the reality and the information in the CDB. The improvement of clarity concerning the CDB application is important in order to minimise the possibility of malformation in the CDB.

3

Modern Factors of Health and Their Peculiarities for Teenagers

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Surmach M. J., Tishchenko E., Piecewicz-Szczęsna H.

Polish Journal of Public Health

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2015

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vol. 124

|

issue 3

152-155

EN

The work aimed at specifying modern features of civilizational factors influence on the health, revealing peculiarities of young age, establishing reflexion of modern factors of health in methodological approaches to health studying. Changes in understanding health are reflected in its studying methodology. The analysis of sociological research data shows, that the social stress became the main reason of medical-demographic situation deterioration in days of reforms. The mechanism of its influence was the loss of effective labor motivation, social envy, and deterioration of spiritual condition of a society. Material well-being decrease was not a determinative factor. The problem of inequalities in health gets the increasing urgency. It is connected with physical and social living environment; availability of qualitative medical aid; specific features of behavior of people. At a medical aid guarantee, and at teenage age, factors of social living environment, which influence behavior in health sphere by means of stigmatization are especially significant.

4

Gender-related incidence, risk factors exposure and survival rates of laryngeal cancers – the 10-years analysis of trends from one institution

80%

Majszyk D., Bruzgielewicz A., Osuch-Wójcikiewicz E., Rzepakowska A., Niemczyk K.

Polish Journal of Otolaryngology

|

2019

|

vol. 73

|

issue 3

6-10

EN

Objectives: The aim of the study was the analysis of the epidemiology of laryngeal cancer over 10 years in relation to known risk factors and to assess the current survival rates in this group of patients. Methods: The data were retrospectively collected from patients’ medical records, then entered in the database using dedicated software and a statistical analysis was performed. Results: 512 subjects - 443 men (86.5%) and 69 women (13.5%) were enrolled into the study. The male-to-female ratio was 6.4:1. There were 97.1% smoking women and 98% smoking men, however the history of more than 20 cigarettes per day smoking admitted 81.1 % of women and 94.6% of men. Heavy alcohol consumption was the case in 14 (20.3%) women and in 307 (69.3%) men. For both the size of heavy alcohol consumption and the size of excessive tobacco use, there was found statistically significant difference between women and men with laryngeal cancer (p<0.05). In the majority of male and female subjects, the tumour was located in the supraglottis/glottis area. Apparently this tumour location was much more common among women, accounting for 60.9% of cases , while in men was confirmed in 39.3% of cases. The stages of the laryngeal cancer were similarly of high advancement for both the men and women - stages III and IV were confirmed in 82.6% of women and in 77.6% of men. The over 5-year survival rate was 39.1% among women and 37.2% among men. Conclusions Contradictory to decreased exposure to risk factors and the shorter period for diagnosis, the higher stages of cancer were observed in women. Although in women the advancement was higher and the majority of cases were located in unfavourable supraglottic area, the survival rates were higher. Key words: laryngeal cancer, epidemiology, men and women, risk factors

5

Trends in the treatment of risk factors for stroke in a Czech stroke unit

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Simunek L., Krajickova D., Vysata O., Valis M.

Open Medicine

|

2014

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vol. 10

|

issue 1

EN

The goal of this study is to evaluate therapeutic trends for several diseases that represent risk factors for stroke. The relative frequency of therapy with compounds that influence the risk factors for stroke was monitored in a group of 3,290 patients who were hospitalised in the Stroke Unit at the University Hospital in Hradec Kralove between 2005 and 2012. For most drugs monitored, the reasons for the significant decrease or increase in use were causes other than the reduction of stroke risk. Despite this finding, the majority of statistically significant changes had, according to review of comparative studies, a posi- tive effect on prevention of stroke. Motivation to change treatment of stroke risk factors, such as hypertension, diabetes mellitus and hypercholesterolemia, was mainly aimed at sufficient disease management with a minimum of adverse effects. On the other hand, optimization of stroke recurrence and economic factors were motivations to treatment changes in prevention with antiplatelets. Antidiabetics were associated with an increase in met- formin use and reduction in insulin use. For antihyperten- sives, the most significant reduction was associated with the use of diuretics, although calcium channel blockers and beta-blockers are also less used. Additionally, the use of the ACE inhibitor ramipril increased

6

Retrospective evaluation of risk factors for oral cavity and oropharynx cancers in patients under the program of head and neck cancers prevention

80%

Kowalski A., Olszewski J., Zielińska-Bliźniewska H.

Otolaryngologia Polska

|

2019

|

vol. 73(6)

24-31

EN

Introduction: The aim of the study was to analyze the risk factors for oral cavity and pharyngeal cancer in people examined under the Head and Neck Cancer Prophylaxis Program. Material and methods: The study was conducted in a total of 300 patients, including 186 women and 114 men, as part of the Head and Neck Cancer Prevention Program in 2014–2018. Before the laryngological examination, the patients completed a demographic and medical questionnaire regarding the risk factors of head and neck cancer, including education, reported disease symptoms, smoking addiction, number of cigarettes smoked daily, alcohol consumption, frequency of visits in a dental office, oral hygiene measures, number of sexual partners, oral sex, family medical history of head and neck cancer. Results: The subjects reported the following symptoms: hoarseness 43.33%, difficulty swallowing 21.33%, pain or mouth burning 20.33% and other symptoms were observed in 46.33%. The main dental symptoms were: bleeding from the gums during teeth brushing in 48.89%, dry mouth 45.56%. Currently 20.33% of respondents smoke, whereas 54% of patients smoked in the past. In the analyzed material, the majority (80%) consumed alcoholic beverages. 27.67% of respondents admitted having oral sex, including 24.73% of women and 32.46% of men. After performing the extended diagnostics, the tumor was found in 10% of the subjects. C onclusions: Statistical significance of differences was found: between hoarseness and alcohol consumption, both in women and in men, between hoarseness and smoking in women, between difficulty in swallowing and smoking in women, between burning/pain in the mouth and smoking in men, between hoarseness and the cultivation of oral sex in men, between the difficulty of swallowing and the practice of oral sex in the studied men and between burning/pain in the oral cavity and the occurrence of malignancy.

7

A levels of endogenous gonadal hormones and their relationship with selected coronary artery disease risk factors among young women post myocardial infarction

80%

Ablewska U., Jankowski K., Rzewuska E., Liszewska-Pfejfer D., Hryniewiecki T.

Acta Biochimica Polonica

|

2011

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vol. 58

|

issue 3

385-389

EN

In recent decades a significant raise in the incidence of myocardial infarction among young women has been recorded. It is presumed that, apart from the classical risk factors, other reasons exist for premature atherosclerosis in young women, related to the homeostasis of gonadal hormones. The aim of the study was to analyze the levels of gonadal hormones (estradiol, progesterone, follicle-stimulating hormone, luteinizing hormone, testosterone and dehydroepiandrosterone) measured in the luteal phase, in 65 normally menstruating women post myocardial infarction (MI) and to investigate a possible relationship between the hormone profile and selected coronary artery disease (CAD) risk factors. The levels of gonadal hormones: estradiol, progesterone, follicle-stimulating hormone, luteinizing hormone, testosterone and dehydroepiandrosterone were measured in the luteal phase. All examined women had normal mean levels of gonadal hormones. In the post MI patients leading a sedentary life style, a significantly lower mean progesterone concentration was observed (16.29 ± 9.11 versus 29.43 ± 21.14 nmol/l, p < 0.05) and significantly higher mean testosterone concentration (2.34 ± 0.98 versus 1.76 ± 1.09 nmol/l, p < 0.05) when compared to patients from the same group, but leading a more active life. In obese post MI women (BMI ≥ 30 kg/m2) a lower mean concentration of progesterone was detected (18.02 ± 8.12 versus 26.16 ± 14.72 nmol/l, p < 0.05), than in slimmer patients from the same group. In post MI women with a positive family history for CAD, a significantly higher mean concentration of testosterone was detected (2.31 ± 1.22 versus 1.67 ± 0.74 nmol/l, p < 0.05) than in patients with no family history. The results suggest a correlation between levels of gonadal hormones and classical CAD risk factors.

8

Risk factors for impaired wound healing and prolonged hospitalization in patients after amputation of the lower limb above the knee joint

80%

Orłowski M., Pluta P., Kowalczyk A., Kasprzak-Szczepańska K., Pająk M., Dziki A.

Polish Journal of Surgery

|

2019

|

vol. 91(5)

27-33

EN

ntroduction: Lower limb amputation is a surgery performed as a last resort, when all other therapeutic options have been exhausted. The duration of treatment lasts from a few to several months and depends on the extent of amputation, the patient's overall health and the course of the stump healing process. Materials and methods: A retrospective analysis was performed using the database of the General and Vascular Surgery Ward of the Nikolay Pirogov Regional Specialist Hospital in Łódź. Patients who underwent lower limb amputation at the transfemoral level in 2017 were analyzed. 92 patients undergoing surgery were qualified for the study. Patients were divided into two groups: those with no healing complications and those with stump healing complications. Medical records of both groups were analyzed for risk factors for impaired healing. The obtained data were subjected to statistical analysis. Results: Patients with impaired stump healing most often had minimal bleeding and higher ASA scores compared to patients without healing complications. No differences between the two groups were found for the remaining parameters. Patients with complications needed an average of 28 days to heal the wound and spent an average of 40 days in hospital, compared to 14 and 21 days, respectively, for patients without complications. The percentage of deaths in the group of patients with complications was also significantly higher (35%) than in the group of patients without complications (5%). Conclusions: Statistically significant factors increasing the risk of impaired stump healing include high ASA scale and minimal muscle bleeding during surgery. Patients who experienced this complication are at greater risk of prolonged hospitalization and death in the postoperative period. This study showed statistically significant risk factors for impaired stump healing following amputation and confirmed the negative impact of this complication on the length of hospitalization and risk of death.

9

Factors associated to burn-out among Ibn Sina Hospital public health professionals

80%

Chtibi H., Mammad K., Alaoui A. M., Mohammed O., Jamila R., Touhami Ahami A. O.

Acta Neuropsychologica

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2024

|

vol. 22(1)

95-106

EN

Burn-out or exhaustion syndrome is caused by a prolonged exposure to a chronic professional stress. Public Health Professionals are the most exposed to this kind of risk. The ultimate goal here is to determine the prevalence of the burn-out and search for factors associated with this pathology among those who work in the field of health. Our sample, which is from the Ibn Sina Hospital in Rabat, consists of 150 nurses, 80 doctors, and 40 administrators. A self-questionnaire was employed, the Maslach Burnout Inventory (MBI) as well as a clinical interview. The results of this study show a high degree of burnout. Moreover, 56.66% of participants show a high level of emotional exhaustion, 45.18% suffer from a high level of depression. Meanwhile, the loss of a sense of personal accomplishment is high among 48.51% of those surveyed. The emotional exhaustion observed among people who have worked for a long time ago is associated with the means of transportation used and to the unsuitable hours of work. Depersonalization exists among elderly people and the oldest at work. This study confirms the existence of a high level of burnout among health professionals. Many socio-demographic and socio-professional factors contribute to the increase in the level that people are affected. These factors encourage the promotion of better working life conditions.

10

Gender-related incidence, risk factors exposure and survival rates of laryngeal cancers – the 10-years analysis of trends from one institution

80%

Majszyk D., Bruzgielewicz A., Osuch-Wójcikiewicz E., Rzepakowska A., Niemczyk K.

Otolaryngologia Polska

|

2019

|

vol. 73(3)

6-10

EN

Objectives: The aim of the study was the analysis of the epidemiology of laryngeal cancer over 10 years in relation to known risk factors and to assess the current survival rates in this group of patients. Methods: The data were retrospectively collected from patients’ medical records, then entered in the database using dedicated software and a statistical analysis was performed. Results: 512 subjects - 443 men (86.5%) and 69 women (13.5%) were enrolled into the study. The male-to-female ratio was 6.4:1. There were 97.1% smoking women and 98% smoking men, however the history of more than 20 cigarettes per day smoking admitted 81.1 % of women and 94.6% of men. Heavy alcohol consumption was the case in 14 (20.3%) women and in 307 (69.3%) men. For both the size of heavy alcohol consumption and the size of excessive tobacco use, there was found statistically significant difference between women and men with laryngeal cancer (p<0.05). In the majority of male and female subjects, the tumour was located in the supraglottis/glottis area. Apparently this tumour location was much more common among women, accounting for 60.9% of cases , while in men was confirmed in 39.3% of cases. The stages of the laryngeal cancer were similarly of high advancement for both the men and women - stages III and IV were confirmed in 82.6% of women and in 77.6% of men. The over 5-year survival rate was 39.1% among women and 37.2% among men. Conclusions Contradictory to decreased exposure to risk factors and the shorter period for diagnosis, the higher stages of cancer were observed in women. Although in women the advancement was higher and the majority of cases were located in unfavourable supraglottic area, the survival rates were higher. Key words: laryngeal cancer, epidemiology, men and women, risk factors

11

Risk factors for poor prognosis in heart failure with particular attention to the elderly population

80%

Dobrowolska M., Miękus P., Świątczak M., Raczak G., Daniłowicz-Szymanowicz L.

European Journal of Translational and Clinical Medicine

|

2021

|

vol. 4

|

issue 2

18-30

EN

Background: Heart failure (HF) is a leading cause of poor outcome. Age is considered one of the most critical risk factors for both the incidence and prognosis of HF. Therefore we aimed to assess the predictors of poor prognosis in HF patients with particular attention to the elderly population. Material and methods: We retrospectively enrolled patients hospitalized due to HF exacerbation during 2016-2017 (203 patients). The end-points were all-cause mortality and emergency rehospitalizations within a two-year follow-up period. A detailed analysis was performed in the subgroups of patients younger and older than 65 years old. Results: 121 (60%) patients experienced the end-points. Age, low systolic blood pressure, NYHA class IV, right ventricle HF symptoms, high C-reactive protein, troponin, NT-proBNP, hyponatremia, catecholamine therapy and mechanical ventilation during hospitalization independently predicted the end-points. The elderly were characterized by a higher incidence of concomitant diseases and HF with moderately reduced or preserved LVEF, worse laboratory parameters and pharmacological treatment, as well as worse prognosis. Conclusion: The prognosis of patients hospitalized due to HF, mainly the elderly, is poor. Simple clinical parameters could be useful in further decision-making regarding the intensification of their treatment.

12

The value of pedigrees and clinical assessment in identification of a high risk cancer group – our experience

80%

Jaworowska E.

Polski Przegląd Otorynolaryngologiczny

|

2016

|

vol. 5(2)

51-56

EN

Pedigree and clinical data are still very important diagnostic tool useful in estimation of a high risk of a cancer devel-opment, molecular basis research and also determining optimal screening for a single family. In this study the own experience was presented in identification of the risk of cancer prevalence with different organ location among the first degree relatives of 760 patients with laryngeal cancer.

13

The role of biomarkers in early prediction and molecular mechanisms of preeclampsia

80%

Bhaskar Kalarani I., Veerabathiran R., Mohammed V.

European Journal of Translational and Clinical Medicine

|

2022

|

vol. 5

|

issue 2

57-66

EN

Preeclampsia (PE) is determined as high blood pressure during pregnancy and proteinuria of 300 mg or more in a 24-hour urine sample. PE is a leading cause of maternal death, with about 55000 deaths worldwide each year. Toxic substances that damage the maternal vascular endothelium induced PE, resulting in liver and kidney malfunction. It is crucial for obstetricians to identify as early as possible the patients who are at risk for PE. Familial history of PE, polycystic ovarian disease, sleeping disorders, urinary infections, periodontal disease, smoking, and lifestyle are the major risk factors involved in this disease. VEGF, sFlt1, sENG, PAPP-A, inhibin A and activin A proteins, fetal hemoglobin, heat shock protein and placental protein have been shown to predict or diagnose PE and help in understanding the pathogenesis of PE. In addition, a better understanding of PE pathogenesis would aid in identifying the most effective treatments that do not impair the fetus’ prognosis. The aim of our study is a review of the pathophysiology and biomarkers, such as pro- and anti-angiogenic substances, that may be useful in the detection of PE in the future.

14

Risk factors of pancreatitis after endoscopic sphincterotomy. Review of literature and practical remarks based on approximately 10,000 ERCPs

80%

Jamry A.

Polish Journal of Surgery

|

2017

|

vol. 89(5)

29-33

EN

Post-endoscopic pancreatitis (PEP) is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP). Depending on the presence of risk factors, PEP can occur in 4,1% to about 43% of patients. According to the European Society of Gastrointestinal Endoscopy (ESGE) guidelines, only three to patient-associated risk factors have been identified: suspected sphincter of Oddi dysfunction (SOD) (OR 4.09), female gender (OR 2.23), and previous pancreatitis (OR 2.46). Another three procedure-associated factors include cannulation attempt duration > 10 minutes (OR 1.76), more than one pancreatic guidewire passage (OR 2.77, CI: 1.79 – 4.30), and pancreatic injection (OR 2.2, CI: 1.60 – 3.01). Importantly, analyses of cumulative risk due to coexistence of several factors emphasize the importance of female sex, difficult cannulation, CBD diameter <5 mm, young age, and many other factors. Unfortunately, studies performed to date have included only small numbers of patients with several co-existing risk factors. Therefore, further analysis of other risk factors and the cumulative risk related to their co-occurrence is necessary. Based on current evidence, special care must be given to patients with several risk factors. Also, care should be given to proper qualification of patients, use of guidewires, early pre-cut incision, protective Wirsung’s duct stenting, and rectal NSAID administration.

15

Prevalence and risk factors of urinary incontinence in women

80%

Wierzbicka M., Urban K., Murawski M., Wronecki K.

Physiotherapy

|

2009

|

vol. 17

|

issue 1

38-44

PL

Nietrzymanie moczu (Urinary Incontinence - UI) u kobiet zostało uznane za chorobę społeczną ponieważ dotyczy ona ponad 5% społeczeństwa. Częstość występowania wysiłkowego nietrzymania moczu u kobiet w różnych grupach wiekowych szacuje się na 22 do 45%. Cel pracy: W pracy podjęto próbę oceny występowania i czynników ryzyka nietrzymania moczu u kobiet. Materiał i metody: Badania przeprowadzono u 17 pacjentek z wysiłkowym nietrzymaniem moczu, które zostały zakwalifikowane do zabiegu operacyjnego leczenia wysiłkowego nietrzymania moczu. U wszystkich przeprowadzono wywiad, badanie ginekologiczne i diagnostykę urodynamiczną. Spośród czynników ryzyka analizowano: wiek, BMI, przeszłość położniczą (przebyte porody, poronienia i cięcia cesarskie) oraz operacje urologiczne i ginekologiczne. Wyniki: Średni wiek pacjentek wyniósł 55,6 roku (37-79). Wartość BMI średnio wynosił 27 (otyłość). Wszystkie pacjentki były aktywne zawodowo, w większości były wieloródkami. Przeszłość operacyjną odnotowano w 9 przypadkach. Wnioski: Czynniki ryzyka występowania wysiłkowego nietrzymania moczu sklasyfikowano jako uroginekologiczne, konstytucjonalne i środowiskowe (np. okres pomenopauzalny, liczne porody, obciążająca praca fizyczna, podwyższony wskaźnik masy ciała, operacje w miednicy mniejszej). Wnikliwa analiza czynników ryzyka pozwoliła na poznanie patogenezy choroby, wpływu czynników środowiskowych, kulturowych i anatomicznych oraz opracowanie metod zapobiegania występowania choroby i poprawy wyników leczenia.

EN

Urinary Incontinence (UI) in women has been claimed a social disease as its frequency has exceeded 5 %. Its prevalence is estimated in different age ranges as 22 to 45 %. Aim of the study: assessment of the prevalence and risk factors of urinary incontinence in women. Material and Methods: The tests covered 17 women with exercise urinary incontinence, who had been qualified for surgery. The evaluation included an interview, gynecological examination and urodynamic diagnostics. The following risk factors were analyzed: age, body mass index (BMI), obstetrical history (labours, abortions, Caesarean sections) urological and gynecological operations. Results: Mean age of patients was 55,6 years (37-79). The value of BMI (body mass index) was 27 (obesity). All patients were professionally active, most of them were multiparas. 9 of them had been undergone a surgery in the past. Conclusions: The Urinary Incontinence risk factors were classified as urogynaecological constitutional, neurological and environmental (for example postmenopausal period, numerous labours, exhausting physical work, increased BMI, minor pelvis surgery in the past). In-depth analysis of all urinary incontinence risk factors allowed the authors to recognize the disease pathogenesis, the influence of environmental, cultural, genetic and anatomic factors and to prepare methods of prevention and improvement of treatment results.

16

Predictive factors for preeclampsia in pregnant women: a unvariate and multivariate logistic regression analysis

80%

Direkvand-Moghadam A., Khosravi A., Sayehmiri K.

Acta Biochimica Polonica

|

2012

|

vol. 59

|

issue 4

673-677

EN

Introduction: Several risk factors have been used to predict preeclampsia. The role of some risk factors as predictors associated with preeclampsia among Iranian women was analyzed in the present study using logistic regression. Materials and Methods: 610 women attending the obstetric ward of Mustafa hospital in Ilam were enrolled in this study. Demographic variables such as age, Body Mass Index (BMI), medical and obstetrics variables such as education, number of pregnancy, abortion and parity from May to September 2010 were analyzed. We used the unvaried and multiple logistic regression analyses to predict preeclampsia. Results: The history of preeclampsia, hypertension, and infertility showed to be good independent predicator variables for preeclampsia using multivariate logistic regression analysis (OR was 5.46, 2.34 and 3.07 respectively). Area Under the Receiver Operation Character (AUROC) was estimated to be 0.67 (95% CI 0.59-0.67, p<0.01) indicating the efficacy of the model for the prediction. Conclusion: The history of preeclampsia, hypertension and infertility predict preeclampsia with an increased odds ratio. Using such variables in regression analysis can help to diagnose preeclampsia beforehand and hence allow timely intervention.

17

Analysis of risk factors for oral cavity and oropharynx cancer in the authors’ own material

80%

Nowosielska-Grygiel J., Owczarek K., Bielińska M., Wacławek M., Olszewski J.

Polish Journal of Otolaryngology

|

2017

|

vol. 71

|

issue 2

23-28

EN

Introduction: The aim of the study was to analyse the risk factors for oral cavity and oropharynx cancer in peopled examined under the Head and Neck Cancer Awareness Week in 2016, Lodz. Material and methods. In Lodz, 21st September 2016, under the Head and Neck Cancer Awareness Week, 106 people, including 67 women aged 29–77 and 39 men aged 23–84, underwent preventive examinations in the hospital department. Prior to the laryngological examination, the patients were asked to answer questions that referred to their education, medical case history, symptoms, smoking habits with the number of cigarettes per day, alcohol intake, the number of lifetime sexual partners, oral sex engagement, incidents of head and neck cancer in the family history. Results: The major part of the examined patients were women and men with the secondary and high level of education, 47,76% and 35,82%, and 58,97% and 35,91% respectively. The patients were informed by mass media about the planned preventive medical examinations – 80,60% women and 79,49% men. The most common symptoms reported by women were: hoarse voice in 61,19% cases, dysphagia in 32,84% cases and burning sensation and/or pain in the oral cavity in 29,85% cases. The examined male patients mainly showed hoarse voice (46,15%), other symptoms (43,59%) and dysphagia (25,64%). 28,35% women and 28,20% men smoked cigarettes, while passive smokers were 22,38% and 25,64% respectively. Alcohol consumption was reported by 67,16% women and 82,05% men, rather occasionally. Having oral sex was noted in 25,37% women and 38,46% men, mostly with multiple sexual partners. Among the studied patients, 13,43% women and 5,12% men suffered from malignant cancer, including 2,98% women and 2,56% men who reported head and neck carcinoma in the medical interview. On the basis of the interview and ENT examination, 11,94% women and 17,94% men were qualified for the extended oncological diagnostics. Conclussion. The Fourth Head and Neck Cancer Awareness Week shows the increased interest in preventive screening, especially oncological screening, and thus the necessity of such preventive activities in the future.

18

The effectiveness of screening for major cardiovascular risk factors in the population of small towns in Poland

80%

Rutkowski M., Wierucki Ł., Wojciechowska A., Zdrojewski T.

European Journal of Translational and Clinical Medicine

|

2021

|

vol. 4

|

issue 1

57-64

EN

Background: Screening represents an important tool to improve detection of cardiovascular risk factors. Uniform standards for screening programs and for evaluation of their effectiveness are still lacking. Material and methods: The results of the Polish 400 Cities Project (P400CP) were analyzed by age and gender, and with regard to the prevalence and awareness of cardiovascular risk factors. The P400CP population were volunteers reporting for screening tests in small towns, and a representative sample was used as control. Results: Mean age in the screening group was 10 years more than in the representative sample. Two thirds of participants were women. First-time diagnosis rates for elevated arterial blood pressure, hyperglycemia and hypercholesterolemia in the screening were 28%, 15% and 51%, respectively. Almost 40% of participants reported previously diagnosed hypertension (vs. 25% of the control sample), 7% vs. 4% reported diabetes and 16% vs. 9% – hypercholesterolemia. Smokers represented 16.5% of participants (36% of the control sample). Conclusions: “Open” screening programs fail in targeting young adults, especially males, and people reporting for screening are often already diagnosed with arterial hypertension and/or diabetes. Despite these limitations, “open” screening is effective in detecting undiagnosed cases of hypercholesterolemia. Non-smokers report for screening tests more often.

19

Clostridium difficile infection in patients hospitalized in the gastroenterology ward – retrospective analysis

80%

Podlaszewska K., Ewa M. P., Gąsiorowska A.

Polish Journal of Surgery

|

2018

|

vol. 90(1)

7-12

EN

INTRODUCTION. Clostridium difficile associated colitis became over last years a worldwide medical issue. It involves patients of the Polish hospitals too. The aim of the study was the analysis of CDAD incidence and the course of infection in Gastroenterology Ward of Regional Specialist Hospital of Zgierz, 2012-2015. MATERIAL AND METHODS. Retrospective analysis of the medical documentation of 79 patients with CDAD was performed. Demographic and epidemiological data and the clinical course of infection were analyzed. RESULTS. The study group comprised of women in 59,5% and men in 40,5%. The patients’ average age was 70,5 years. The average hospitalization period was 10,3 days. CDAD infection seasonality was proved, with statistically significant peak in springtime. 73% of patients were previously hospitalized and 85% - had co-morbidities. 76% of patients underwent antibiotherapy, whilst 29% - used PPI prior to CDAD diagnosis. 50,6% of patients had severe CDAD diagnosed. The recurrence reached 14%. In 19% of patients CDAD resulted in death. DISCUSSION. The results of the study confirm increase of the incidence of the patients with CDAD in Gastroenterology Ward over 4-years’ observation. The prevalence was higher among 65+ patients, after prior hospitalization and antibiotherapy. The co-morbidities was a significant risk factor, especially common in severe cases. CONCLUSION. The results we obtained confirm substantial importance of Clostridium difficile infection leading to antibiotherapy-associated diarrhea among adults, causing prolonged hospitalization, increased prevalence and mortality of patients. Getting to know and minimizing the risk factors will prevent the future outbreak of the disease.

20

Retrospective evaluation of risk factors for oral cavity and oropharynx cancers in patients under the program of head and neck cancers prevention

80%

Kowalski A., Olszewski J., Zielińska-Bliźniewska H.

Polish Journal of Otolaryngology

|

2019

|

vol. 73

|

issue 6

24-31

EN

Introduction: The aim of the study was to analyze the risk factors for oral cavity and pharyngeal cancer in people examined under the Head and Neck Cancer Prophylaxis Program. Material and methods: The study was conducted in a total of 300 patients, including 186 women and 114 men, as part of the Head and Neck Cancer Prevention Program in 2014–2018. Before the laryngological examination, the patients completed a demographic and medical questionnaire regarding the risk factors of head and neck cancer, including education, reported disease symptoms, smoking addiction, number of cigarettes smoked daily, alcohol consumption, frequency of visits in a dental office, oral hygiene measures, number of sexual partners, oral sex, family medical history of head and neck cancer. Results: The subjects reported the following symptoms: hoarseness 43.33%, difficulty swallowing 21.33%, pain or mouth burning 20.33% and other symptoms were observed in 46.33%. The main dental symptoms were: bleeding from the gums during teeth brushing in 48.89%, dry mouth 45.56%. Currently 20.33% of respondents smoke, whereas 54% of patients smoked in the past. In the analyzed material, the majority (80%) consumed alcoholic beverages. 27.67% of respondents admitted having oral sex, including 24.73% of women and 32.46% of men. After performing the extended diagnostics, the tumor was found in 10% of the subjects. C onclusions: Statistical significance of differences was found: between hoarseness and alcohol consumption, both in women and in men, between hoarseness and smoking in women, between difficulty in swallowing and smoking in women, between burning/pain in the mouth and smoking in men, between hoarseness and the cultivation of oral sex in men, between the difficulty of swallowing and the practice of oral sex in the studied men and between burning/pain in the oral cavity and the occurrence of malignancy.

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