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  1. 1 Biotechnologia

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  1. 1 2008

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  1. 1 Sikorski M. M.

  2. 1 Woronowicz W. W.

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Application of DNA microarray technology in studies of human allergy

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Woronowicz W. W., Sikorski M. M.
Biotechnologia
|
2008
|
issue 4
115-130
EN
Allergy is a complex genetic disorder contributing numerous genes, especially involved in Th2 immunity and IgE synthesis. Additional, environmental factors like: allergens exposure, cigarette smoke, pollutants, infectious agents and many others, have influence in allergy development. With DNA microarray technology it is possible to search for genes expression profiles of all interacting genes in pararel and learn more about the mechanism of allergy. These research include genes expression profiling of different model organisms (human, mice, monkey) and cell cultures.
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