EQUILIBRIUM SWELLING STUDY OF CROSSLINKED CHITOSAN MEMBRANES IN WATER, BUFFER AND SALT SOLUTIONS

• Authors: Magdalena Gierszewska , Jadwiga Ostrowska-Czubenko
• Languages of publication: EN

Abstracts

EN

Physically crosslinked membranes were prepared by treating chitosan (Ch) with pentasodium tripolyphosphate (TPP) at different reaction conditions. The equilibrium swelling ratio, Seq, of Ch/TPP membranes in water, buffer and salt solutions at 37 C were determined. The experimental data indicated, that Seq depended on pH of buffer solution and type and concentration of salt solution. Swelling capacity in water depended on the content of TPP ions in the membrane and crosslinking density

Keywords

EN

chitosan; crosslinking; equilibrium swelling; membranes

• Publisher: Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
• Journal: Progress on Chemistry and Application of Chitin and its Derivatives
• Year: 2016
• Volume: 21
• Pages: 55-62

Contributors

author

Magdalena Gierszewska

• Faculty of Chemistry, Nicolaus Copernicus University in Toruń Gagarina St. 7, 87-100 Toruń, Poland

author

Jadwiga Ostrowska-Czubenko

• Faculty of Chemistry, Nicolaus Copernicus University in Toruń Gagarina St. 7, 87-100 Toruń, Poland

References

• [1] Peppas NA; (2004) Hydrogels. In: Ratner BD, Hoffman AS, Schoen FJ, Lemons JE (eds), Biomaterials Science: An Introduction to Materials in Medicine, 2nd edn. Academic Press, New York, 100-107.
• [2] Struszczyk MH; (2002) Chitin and. Chitosan, Part I. Properties and production. Polimery (Warsaw) 47, 316-325.
• [3] Berger J, Reist M, Mayer JM, Felt O, Peppas NA, Gurny R; (2004) Structure and interactions in covalently and ionically crosslinked chitosan hydrogels for biomedical applications. Eur J Pharm Biopharm 57, 19-34. DOI:10.1016/S0939-6411(03)00161-9
• [4] Chakrabarty T, Kumar M, Shahi VK (2010). In: Elnashar M (ed), Biopolymers, InTech, Chapter 10, 201-226. http://www.intechopen.com/articles/show/title/chitosan-based-membranes
• [5] Gierszewska-Drużyńska M, Ostrowska-Czubenko J; (2011) Influence of crosslinking process conditions on molecular and supermolecular structure of chitosan hydrogel membrane. In: Jaworska M (ed), Progress on Chemistry and Application of Chitin and its Derivatives, Vol. XVI, Polish Chitin Society, Łódź, 15-22.
• [6] Muzzarelli RAA, Rocchetti R, Stanic V, Weckx M; (1997) Methods for the determination of the degree of acetylation of chitin and chitosan. In: Muzzarelli RAA, Peter MG (eds), Chitin Handbook, Atec Edizioni, Grottammare, 109-119.
• [7] Il̀ina AV, Varlamov VP; (2004) Hydrolysis of chitosan in lactic acid. Appl Biochem Microbiol 40, 300-303. DOI: 10.1023/B:ABIM.0000025956.98250.30
• [8] Ostrowska-Czubenko J, Pieróg M. Gierszewska-Drużyńska M; (2013) Water state in chemically and physically crosslinked chitosan membranes. J Appl Polym Sci 130, 1707-1715. DOI: 10.1002/app.39357
• [9] Peppas NA, Khare AR; (1993) Preparation, structure and diffusional behaviour of hydrogels in controlled release. Adv Drug Deliver Rev 11, 1-35. DOI:10.1016/0169-409X(93)90025-Y
• [10] Peppas NA, Bures P, Leobandung W, Ichikawa H; (2000) Hydrogels in pharmaceutical formulations. Eur J Pharm Biopharm 50, 27-46. DOI:10.1016/S0939-6411(00)00090-4
• [11] Baipai SK, Singh S; (2006) Analysis of swelling behaviour of poly(methacrylamide-co-methacrylic acid) hydrogels and effect of synthesis conditions on water uptake. React Funct Polym 66, 431-440. DOI: 10.1016/j.reactfunctpolym.2005.09.003
• [12] Mudassir J, Ranjha NM; (2008) Dynamic and equilibrium swelling studies: crosslinked pH sensitive methyl methacrylate-co-itaconic acid (MMA-co-IA) hydrogels. J Polym Res 15,195-203. DOI: 10.1007/s10965-007-9159-x
• [13] Shu XZ, Zhu KJ; (2002) The influence of multivalent phosphate structure on the properties of ionically cross-linked chitosan films for controlled drug release. Eur J Pharm Biopharm 54, 235-243. DOI:10.1016/S0939-6411(02)00052-8
• [14] Mi FL, Shyu SS, Wong TB, Jang SF, Lee ST, Lu KT; (1999) Chitosan–polyelectrolyte complexation for the preparation of gel beads and controlled release of anticancer drug. II. Effect of pH-dependent ionic crosslinking or interpolymer complex using tripolyphosphate or polyphosphate as reagent. J Appl Polym Sci 74, 1093-1107. DOI: 10.1002/(SICI)1097-4628(19991031)74:5<1093::AID-APP6>3.0.CO;2-C
• [15] Norouzi HR, Azizpour H, Sharafoddinzadeh S, Barati A; (2011) Equilibrium swelling study of cationic acrylamide-based hydrogels: Effect of synthesis parameters, and phase transition in polyelectrolyte solutions. J Chem Petrol Eng (University of Teheran) 45, 13-25.
• [16] Wiberg E, Wiberg N; (2001) Holleman-Wiberg Inorganic Chemistry. Academic Press, London.

• Document Type: article