EN
Oxidative stress is known top-lay an important role in the development and pathogenesis of several chronic diseases such as diabetes, neurodegenerative diseases, and cancer. Exposure to poisons and toxicants results in the generation of pro-oxidant which eventually cause dysfunction in enzymatic activities and defect in the DNA, resulting to alteration in the expression of genes the induction of oxidative stress is by far associated with modern life styles which include the consumption and exposure to chemicals which are used to preserve and process food. Hence, this review provides insight to the relationship between reactive oxygen species and some chronic disorders. That is the contribution of reactive oxygen species to the pathogenesis of some diseases.