NEW CHITOSAN WOUND DRESSING – FIRST STEP - THE CYTOTOXICITY EVALUATION

• Authors: Ewa Karuga , Adam Zając , Zbigniew Rybak , Jerzy Hanuza
• Languages of publication: EN

Abstracts

EN

The cytotoxicity of chitosan with polyvinox (PCH) and crosslinked chitosan (CH) was studied and analyzed. Cell viability was determined by thiazolyl blue formazan (MTT) assay and cell morphology observations were carried out during cell culturing and MTT tests. Crosslinked chitosan was used as a protective foil (scaffold) for skin wounds. Studies in vitro and the other obtained in this work results prove that the studied materials CH and PCH do not cause cytotoxic activity to Balb 3T3 mouse fibroblasts. CH and PCH are promising biomaterials with prospective application as wound healing dressings.

Keywords

EN

chitosan; cytotoxicity; wound dressing

• Publisher: Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
• Journal: Progress on Chemistry and Application of Chitin and its Derivatives
• Year: 2015
• Volume: 20
• Pages: 97-109

Contributors

author

Ewa Karuga

• Department for Experimental Surgery and Biomaterials Research, Wroclaw Medical University, ul. Poniatowskiego 2, 50-326 Wrocław, Poland

author

Adam Zając

• Faculty of Engineering and Economics, Wrocław University of Economics, ul. Komandorska 118/120, 53 - 345 Wrocław, Poland

author

Zbigniew Rybak

• Department for Experimental Surgery and Biomaterials Research, Wroclaw Medical University, ul. Poniatowskiego 2, 50-326 Wrocław, Poland

author

Jerzy Hanuza

• Faculty of Engineering and Economics, Wrocław University of Economics, ul. Komandorska 118/120, 53 - 345 Wrocław, Poland

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• Document Type: article