Review on pharmacological and biological properties of Acalypha fruticosa Forssk

• Authors: k Roja , Benchilo Ezung , P. Agastian
• Languages of publication: EN

Abstracts

EN

In recent times the years of conventional medicine as an alternate source for the ailment of human health and improvement of microbial resistance to the available antibiotics have recently reaffirmed the need for medicinal plants to test the antimicrobial activity. Acalypha fruticosa is one such plant that is widely known as “Chinnichedi” and shrub belonging to the Euphorbiaceae family is “Birch leaved Acalypha. The leaves and roots are used for treat skin diseases, wounds, stomach problems and poisonous bites. In view of this the present study was investigated to review the Phytochemistry, Pharmacological activity, medicinal properties and biological properties of Acalypha fruticosa.

Keywords

EN

Acalypha fruticosa; Medicinal; Pharmacological; Phytochemistry

Discipline

• BOTANY: BOTANY

• Publisher: Scientific Publishing House „DARWIN”
• Journal: World News of Natural Sciences
• Year: 2022
• Volume: 42
• Pages: 85-93

Contributors

author

k Roja

• Department of Plant Biology and Biotechnology, Loyola College, Chennai-34, Tamil Nadu, India

author

Benchilo Ezung

• Department of Plant Biology and Biotechnology, Loyola College, Chennai-34, Tamil Nadu, India

author

P. Agastian

• Department of Plant Biology and Biotechnology, Loyola College, Chennai-34, Tamil Nadu, India

References

• [1] Akpomie O.O., Olorungbon S. Antimicrobial screening of Terminalia avicennoides and Acalypha wilkesiana. African Journal of Biotechnology 2011; 10 suppl 2: 180-182
• [2] Ellof, J.N. (1998). Which extractant should be used for the screening and isolation of antimicrobial components from plants? J. Ethnopharmacol 60: 1-6.
• [3] Sofowora, A. (1982). Medicinal plants and traditional medicine in Africa. 1st Edn. New York.: John Wiley and Sons, pp: 256.
• [4] Duraipandiyan, V., Ayyanar, M. and Ignacimuthu, S. (2006). Antimicrobial activity of Some Ethnomedicinal plants used by Puliyar tribe from Tamil Nadu, India. BMC Complement. Altern. Med. 20: 6-35
• [5] Mothana, R.A., Abdo, S.A., Hasson, S., Althawab, F.M., Alaghbari, A. A. and Lindequist, U. (2008). Antimicrobial, antioxidant and cytotoxic activities and Phytochemical screening of some Yemeni medicinal plants. Eviden Based Complement. Altern. Med. 7(3): 323–330
• [6] Malathi Ramaswamy, Sivakumar Duraikannu, Chandrasekar Solaimuthu. (2019). Assessment of anti- snake venom effects of Acalypha fruticosa leaves against Indian saw – scaled viper by using envenomed wistar albino rats. In. J. of Scientific Research in Biological Sciences,Vol. 6, Issue 3, pp. 31-40
• [7] Anandakumar AM, Paulsamy S, Sathishkumar P, and Senthilkumar P. Preliminary phytochemical studies for the quantification of secondary metabolites of medicinal importance in the plant. Acalypha fruticosa Forssk. J Appl Nat Sci. 2009; (11): 41-43
• [8] Gopalakrishnan, S., Saroja, K.,Elizabeth, J.D., 2010. Chemical investigation of aerial parts of Acalypha fruticosa forssk. Derpharma Chem. 2, 383-389
• [9] Gamble, J.S. and Fischer, C.(1958). The Flora of Presidency of Madras. Bishen Singh Mahendra Pal Singh. Dehradun 3: 1329-1331
• [10] Hiremath, S.P., Shrishailappa, B., Swamy, H.K.S., Biradar, J.S.: Antimicrobial activity of various extracts of Acalypha indica (Euphorbiaceae). Ind J Microbiol. 33: 75-77 (1993)
• [11] Thambiraj, J and S. Paulsamy (2011). Antimicrobial screening of stem extract of the folklore medicinal plant, Acalypha fruticosa forssk. International Journal of Pharmacy and Pharmaceutical Sciences 3: 285-287
• [12] L. John Peter Arulanandam, A. John de Britto and V.S. Manickam (2007). In vitro propagation of Acalypha fruticosa forssk, an important medicinal plant. Indian Journal of Botanical Research Ind. J. Bot.Vol. 3(2): 223-228
• [13] Shaza Al-Massarani, Mohamed-I Kotb El-Sayed and Amina El-Shaibany (2019). Antioxidant and anti-proliferative activities of Acalypha fruticosa: Possible elucidated mechanism. Journal of Pharmaceutical Sciences Vol. 32, No. 5, pp. 2041-2050
• [14] AI-Taweel, A.M., El-Shafae, A.M., Perveen, S., Fawzy, G.A., Khan, S.I,. 2015. Anti-inflammatory and Cytotoxic constituents of Bauhinia retusa. Int. J. Pharm. 11, 372-376
• [15] Borenfreund, E., Babich, H., Martin-Alguacil, N., (1990). Rapid Chemoensitivity assay with human normal and tumor cells in vitro. In Vitro Cell Dev Biol. 1990 Nov; 26(11): 1030-1034. doi: 10.1007/BF02624436
• [16] Paunraj, M, Ramesh, V. Sakthivelkumar, S. Veeramani, V and Janarthanan, S., (2016). Larvicidal and enzyme inhibitory effects of Acalypha fruticosa (F.) and Catharanthus roseus L(G) Don. Leaf extracts against Culex quinquefasciatus (say.). Asian Journal of Pharmaceutical and Clinical Research Vol 10, Issue 3, 2017, 213-220. DOI 10.22159/ajpcr.2017.v10i3.16029
• [17] Abbott WS. A method of computing the effectiveness of an insecticide. 1925. J Am Mosq Control Assoc 1987; 3(2): 302-303
• [18] Lingathurai, S,S. Ezhil vendan, M.Gabriel Paulra and S. Ignacimuthu.,(2010). Antifeedant and larvicidal activities of Acalypha fruticosa forssk.(euphorbiaceae) against Plutella xylostella L. Larvae. Journal of King Saud University 23, 11-16
• [19] Pavunraj Manickam, Baskar Kathirvelu, Janarthanan Sundaram, Arumugam Munusamy. Bio-efficacy of crude leaf extracts of Acalypha fruticosa Forssk. Against some agriculturally important insect pests. Asian Pacific Journal of Tropical Disease Volume 4, Supplement 2, 2014, Pages S890-S894, https://doi.org/10.1016/S2222-1808(14)60753-2
• [20] El-Shaibany A, AL-Habori M, Al-Massarani S, Al-Adhl A, Michalsen A. Hypoglycaemic activity of Acalypha fruticosa Forssk extracts in normal rabbits. Trop J Pharm Res 2015; 14(8):1445-1450 doi: 10.4314/tjpr.v14i8.17
• [21] Govindu, S., & Adikay, S. (2014). Evaluation of antiepileptic activity of chloroform extract of Acalypha fruticosa in mice. Pharmacognosy Research, 6(2), 108–112. https://doi.org/10.4103/0974-8490.128970
• [22] Jerome E, Timothy AP. What is Epilepsy? A Comprehensive Textbook. 2nd ed. Philadelphia: Lippincott Williams and Wilkins; 1997. p. 1 7
• [23] Gupta M, Mazumdar UK, Sivahkumar T, Vamis MLM, Karki S, Sambathkumar R, Manikandan L. Antioxidant and anti-inflammatory activities of Acalypha fruticosa. Nig J Natural Prod Med 2003; 7: 25-29
• [24] R.A.A. Mothana, R. Gruenert, U. Lindequist, P.J. Bednarski. Study of the anticancer potential of Yemeni plants used in folk medicine. Die Pharmazie - An International Journal of Pharmaceutical Sciences, Volume 62, Number 4, 1 April 2007, pp. 305-307(3)
• [25] Mohammed A. Alshawsh, Ramzi A. Mothana, Hassan A. Al-Shamahy, Salah F. Alsllami, and Ulrike Lindequist. Assessment of Antimalarial Activity against Plasmodium falciparum and Phytochemical Screening of Some Yemeni Medicinal Plants. Evidence-Based Complementary and Alternative Medicine Volume 6 |Article ID 653926, https://doi.org/10.1093/ecam/nem148
• [26] K. Saroja, J. Dulcy Elizabeth and S. Gopalakrishnan 2007. Acalypha fruticosa Forssk. APotential Wound Healing Drug. In: Symposium on Bioresources in the Development of Medicine. National Facility for Marine Cyanobacteria, Bharathidasan University, Tiruchirappalli. 20. 9. 2007–22.9. 2007
• [27] Rajeswari R, Radha R, Jayshree N. Cytotoxicity evaluation and invitro Hepatoprotective effect on aerial parts of Acalypha fruticosa Forssk. (Euphorbiaceae). IJPI’s Journal of Pharmacognosy and Herbal Formulations 2013; (3): 16-20
• [28] Ma, L.Y., Wei, F., Ma, S.C., Lin, R.C., 2002. Two new chromone glucosides from seleginella ancinata. Chin. Chem. Lett. 13, 748-751
• [29] Park, J.H, Lee, S.U., Kim, S.H., Shin, S.Y., Shin, C.G., Yoo, K.H, Lee, Y.S. 2008. Chromone and Chromanone derivatives as strand transfer inhibitors of HIV-1integrase. Arch. Pham. Res. 31, 1-5
• [30] Yoon, J.S., Lee, M.K., Sung, S.H., Kim,Y.C., 2006. Neuroprotective 2-(2-Phenylethyl) Chromones of Imperatacylindraka. J. Nat. Prod. 69, 290-291
• [31] Raj L, Gadamsetty G, Sarada NC. Comparative studies on in vitro anthelmintic activity of Gymnema sylvestre and Acalypha fruticosa Forssk. Int J Pharm Pharm Sci 2012; 4(1): 107-109
• [32] Sivakumar T, Venkatachala Murthi MN, Kumutha P. Evaluation of anti-tumor and anti-oxidant activity of Acalypha fruticosa in Ehrlich’s ascites carcinoma bearing Swiss Albino mice. Res J Pharmaceut Biol and Chem Sci 2010; 1(4): 191-199
• [33] G.H. Schmelzer. Acalypha fruticosa Forssk. In: Medicinal plants. PROTA, Schmelzer, G.H. & Gurib-Fakim, A. [Eds.] Prota 11[1]: Wageningen Netherlands. 2007

• Document Type: article