Left ventricular thrombus after acute myocardial infarction – case report and literature review

• Authors: Michał Razik , Bartosz Basiaga , Piotr Bator , Katarzyna Mizia-Stec

Title variants

PL

Skrzeplina w lewej komorze po ostrym zawale mięśnia sercowego – opis przypadku i przegląd literatury

• Languages of publication: EN PL

Abstracts

EN

Left ventricular (LV) thrombus is a complication of acute myocardial infarction (AMI), especially in patients with anterior AMI and persistent LV systolic dysfunction. Regardless of the progress in invasive AMI therapy, there are literature data showing the frequency of LV thrombi ranging from 2.7% to 19.2% in patients with anterior ST elevation myocardial infarction (STEMI). LV thrombi formation is associated with endothelial injury, blood stasis, and hypercoagulability. Early diagnosis using transthoracic echocardiography (TTE) and cardiac magnetic resonance (CMR) imaging is crucial. Prevention strategies involve assessing the risk factors and considering anticoagulant therapy in exceptional cases. Treatment involves anticoagulation for up to 6 months in combination with antiplatelet therapy. The study presents the current state of knowledge on LV thrombi, provided with a relevant case report as a practical guideline.

PL

Skrzeplina w lewej komorze (left ventricle – LV) jest jednym z powikłań ostrego zawału mięśnia sercowego (acute myocardial infarction – AMI), zwłaszcza u chorych z AMI ściany przedniej z wtórną do zawału utrzy-mującą się dysfunkcją skurczową LV. Badania wskazują, że pomimo postępów w interwencyjnym leczeniu AMI częstość występowania skrzeplin waha się od 2,7% do 19,2% u pacjentów z AMI z uniesieniem odcinka ST (ST elevation myocardial infarction – STEMI). Tworzenie się skrzeplin w LV wiąże się z uszkodzeniem śródbłonka, zastojem krwi i nadkrzepliwością. Kluczowe znaczenie ma wczesna diagnostyka za pomocą echokardiografii przezklatkowej (transthoracic echocardiography – TTE) i rezonansu magnetycznego serca (cardiac magnetic resonance – CMR). Strategie zapobiegawcze obejmują ocenę czynników ryzyka i rozważenie leczenia przeciwzakrzepowego w wyjątkowych przypadkach. Leczenie obejmuje terapię przeciwzakrzepową przez okres do 6 miesięcy w połączeniu z terapią przeciwpłytkową. W pracy przedstawiono aktualny stan wiedzy na temat pozawałowych skrzeplin w LV, z opisem przypadku jako praktyczną wskazówką.

Keywords

EN

acute myocardial infarction; anticoagulants; antykoagulanty; echocardiography; echokardiografia; left ventricle; lewa komora; magnetic resonance imaging; ostry zawał serca; rezonans magnetyczny; skrzeplina; thrombus

Discipline

• MEDICINE: MEDICINE

• Publisher: Śląski Uniwersytet Medyczny w Katowicach
• Journal: Annales Academiae Medicae Silesiensis
• Year: 2024
• Issue: 78
• Pages: 11–16

Contributors

author

Michał Razik

• Students’ Scientific Club, 1st Department of Cardiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, Poland

author

Bartosz Basiaga

• Students’ Scientific Club, 1st Department of Cardiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, Poland

author

Piotr Bator

• Students’ Scientific Club, 1st Department of Cardiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, Poland

author

Katarzyna Mizia-Stec

• 1st Department of Cardiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, Poland

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• Document Type: article