Long-term disease control during TAS-102 therapy in the VI line treatment in a 73-year-old mCRC patient. A case report

• Authors: Piotr Skalij , Piotr Tokajuk , Stefan Jelski , Marek Wojtukiewicz
• Languages of publication: EN

Abstracts

EN

A case of 73-year-old patient with metastatic colorectal cancer who underwent trifluridine/tipiracil therapy within the VI line was presented. Treatment with trifluridine/tipiracil allowed to achieve stabilization of the existing cancer for nearly 7 months.

Keywords

EN

TAS-102; long-term response; metastatic colorectal cancer

Discipline

• MEDICINE: MEDICINE

• Publisher: Medical Education
• Journal: OncoReview
• Year: 2020
• Volume: 10
• Issue: 1
• Pages: 15-17

Contributors

author

Piotr Skalij

• 1. Department of Oncology, Medical University of Bialystok, Poland. 2. Department of Oncology with Daytime Chemotherapy Unit, Bialystok Oncology Centre, Poland

author

Piotr Tokajuk

• 1. Department of Oncology, Medical University of Bialystok, Poland. 2. Department of Oncology with Daytime Chemotherapy Unit, Bialystok Oncology Centre, Poland

author

Stefan Jelski

• Department of Radiology, Bialostockie Oncology Center

author

Marek Wojtukiewicz

• 1. Department of Oncology, Medical University of Bialystok, Poland. 2. Department of Oncology with Daytime Chemotherapy Unit, Bialystok Oncology Centre, Poland

References

• 1. Mayer RJ, Van Cutsem E, Falcone A et al. Randomized trial of TAS-102 for refractory metastatic colorectal cancer. N Engl J Med. 2015; 372(20): 1909-19.
• 2. Xu J, Kim TW, Shen L et al. Results of a randomized, double-blind, placebo-controlled, Phase III trial of trifluridine/tipiracil (TAS-102) monotherapy in Asian patients With previously treated metastatic colorectal cancer: the TERRA study. J Clin Oncol. 2018; 36(4): 350-8.
• 3. Kwakman JJM, Vink G, Vestjens JH et al. Feasibility and effectiveness of trifluridine/tipiracil in metastatic colorectal cancer: real-life data from The Netherlands. Int J Clin Oncol. 2018; 23: 482-9.
• 4. Cremolini C, Rossini D, Martinelli E et al. Trifluridine/tipiracil (TAS-102) in refractory metastatic colorectal cancer: a multicenter register in the frame of the Italian compassionate use program. Oncologist. 2018; 23: 1178-87.

• Document Type: article