Biomechanical aspects of atherosclerosis

• Authors: Jarosław Wasilewski , Kryspin Mirota
• Languages of publication: PL

Abstracts

PL

Pathogenesis of atherosclerosis is a complex multifactorial process of vascular wall injury. It is widely accepted that the local hemodynamic factors, in particular, disturbed flow and low/ oscillatory shear stress leads to the plaque development. We present a consistent concept of atherosclerosis aetiology, taking into consideration the four main components contributing in the atheroma formation: geometric, hemodynamic, hemorheological, and mechanical risk factors. Exemplary illustrative flow simulation results for formulated concept have been presented. It assumes the pulsatile non-Newtonian fluid flow and uses realistic coronary artery geometry based on medical imaging and segmentation.

Keywords

PL

atherosclerosis pathogenesis, shear stress, computational fluid dynamics

• Publisher: [unknown2]
• Journal: Czasopismo Techniczne
• Year: -

Dates

online

2015-04-28

Contributors

author

Jarosław Wasilewski

author

Kryspin Mirota