Ekspresja P-selektyny na powierzchni płytek krwi indukowana endotoksyną bakteryjną Proteus mirabilis

• Authors: Joanna Saluk-Juszczak , Paweł Nowak , Jacek Golański , Barbara Wachowicz , Wiesław Kaca

Title variants

PL

P-selectin expression on blood platelets induced by endotoxin Proteus mirabilis

Abstracts

EN

P-selectin is stored in the a granules of blood platelets. Following platelet activation by
different agonists, P-selectin is expressed on the cell surface where it mediates adhesion
primarily to leucocytes.The aim of the study was to evaluate the direct effect of Proteus
mirabilis lipopolysaccharides on the P-selectin expression on the platelet surface measured by
cytometric method. The obtained results showed that LPS in vitro induced the expression of
P-selectin (CD62) on platelets. It indicates that endotoxin from Gram-negative bacteria can
activate blood platelets.

• Publisher: Wydawnictwo Uniwersytetu Łódzkiego
• Journal: Acta Universitatis Lodziensis. Folia Biochimica et Biophysica
• Year: 2001
• Volume: 15

Dates

published

2001

Contributors

author

Joanna Saluk-Juszczak

author

Paweł Nowak

author

Jacek Golański

author

Barbara Wachowicz

author

Wiesław Kaca

other

Katedra Biochemii Ogólnej Uniwersytet Łódzki

other

Instytut Kardiologii Akademia Medyczna w Łodzi

Identifiers

URI

http://hdl.handle.net/11089/12036