Selective inhibitors of cyclooxygenase-2 (COX-2)

• Authors: F. Mejza , E. Nizankowska
• Languages of publication: PL

Abstracts

EN

Cyclooxygenase is key enzyme in the prostaglandin synthesis. It exists in two isoforms, which have distinct roles in the organism. Cyclooxygenase-2 (COX-2) participates in the pathophysiology of inflammation. Differences in the molecular structure of cyclooxygenases allowed to develop drug that selectively inhibit that isoform. Recently, selective inhibitors of COX-2 were introduced into therapy, providing new opportunities to the treatment of inflammation.

Keywords

EN

CELECOXIB; CYCLOOXYGENASE; ROFECOXIB

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Publisher: Index Copernicus International
• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 2001
• Volume: 55
• Issue: 2
• Pages: 287-302

Contributors

author

F. Mejza

author

E. Nizankowska

• Document Type: ARTICLE
• Publication order reference: F. Mejza, Klinika Pulmonologii, II Katedra Chorob Wewnetrznych CM UJ, ul. Skawinska 8, 31-066 Krakow, Poland