A prospective study of prenatal mercury exposure from maternal dental amalgams and autism severity

• Authors: D.A. Geier , J.K. Kern , M.R. Geier
• Languages of publication: EN

Abstracts

EN

Dental amalgams containing 50% mercury (Hg) have been used in dentistry for the last 150 years, and Hg exposure during key developmental periods was associated with autism spectrum disorders (ASDs). This study examined increased Hg exposure from maternal dental amalgams during pregnancy among 100 qualifying participants born between 1990.1999 and diagnosed with DSM-IV autism (severe) or ASD (mild). Logistic regression analysis (age, gender, race, and region of residency adjusted) by quintile of maternal dental amalgams during pregnancy revealed the ratio of autism:ASD (severe:mild) were about 1 (no effect) for .5 amalgams and increased for .6 amalgams. Subjects with .6 amalgams were 3.2-fold significantly more likely to be diagnosed with autism (severe), in comparison to ASD (mild), than subjects with .5 amalgams. Dental amalgam policies should consider Hg exposure in women before and during the child-bearing age and the possibility of subsequent fetal exposure and adverse outcomes.

Keywords

EN

ASPERGER'S SYNDROME; AUTISM; DEVELOPMENTAL DELAY; NEURODEVELOPMENTAL DISORDER

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Publisher: Marceli Nencki Institute of Experimental Biology, Polish Academy of Sciences
• Journal: Acta Neurobiologiae Experimentalis
• Year: 2009
• Volume: 69
• Issue: 2
• Pages: 189-197

Contributors

author

D.A. Geier

author

J.K. Kern

author

M.R. Geier

• Document Type: ARTICLE
• Publication order reference: Mark R. Geier, The Genetic Centers of America, Silver Spring, Maryland, USA