Feto-maternal immunoregulation

• Authors: M. Klink , B. Rozalska , W. Rudnicka
• Languages of publication: PL

Abstracts

EN

One of the great mysteries in modern immunology is how extraembryonic membranes escape rejection by maternal immune response, although they express paternal genes/antigenes which should stimulate allogenic recognition and rejection.Generally, two theories try to explain the pregnancy phenomenon.One of them emphasizes the role of immunosuppresive reactions in the protection of the fetus.On the contrary, the "immunotropism" theory insist on the importance of mother's immune antigens of the conceptus.Moreover, the last years abounded in discoveries on molecules regulating cell-cell interaction at the level of the initiation and effect or stage of the immune response.The best examples of such molecules could be extracellular matrix proteins, integrins, interleukins and various growth factors.The discussion of those molecules as regards their role in the protection of the fetus was the main aim of this article.

Keywords

EN

FETO-MATERNAL INTERACTION; IMMUNOREGULATION; PREGNANCY

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 1994
• Volume: 48
• Issue: 5
• Pages: 543-563

Contributors

author

M. Klink

author

B. Rozalska

author

W. Rudnicka

• Document Type: article
• Publication order reference: M.Klink