EN
In this paper we showed age effect on hepatic level of cytochrome P-450.We discussed effects of inductors on this hemoproteine also.Cytochrome P-450 content increased to 1-month of life, but decreased to 4-month.In the oldest rats cytochrome P-450 increased again.Content of this hemoprotein was induced by phenobarbital and ?- naphthoflavone in all examined groups, especially strong in young animals.Induction effect of dexamethasone was observed in 4-20 month of life.d