Soluble THF receptors

• Authors: E. Jablonska
• Languages of publication: PL

Abstracts

EN

Soluble cytokine receptors are more general phenomena and play a wider physiological role in the regulation of the immune system than previously recognized. Soluble TNF receptors - sTNF-Rp55 and sTNF-Rp75 by ability to bind to free TNF-a might play a regulatory role in a variety of normal and abnormal reactions mediated by TNF-a. Increase of sTNF-Rs levels have been observed in the serum of patients with a different diseases. Measurement of soluble TNF receptors concentrations seems to be a significant indicator in prognostic estimation of some diseases. Additionally, bioengineered soluble receptors may prove useful as specific cytokine-inhibiting therapeutic agents.

Keywords

EN

CYTOKINE RECEPTOR; TNF RECEPTOR

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 1997
• Volume: 51
• Issue: 5
• Pages: 567-575

Contributors

author

E. Jablonska

• Document Type: article
• Publication order reference: E.Jablonska, Zaklad Immunopatologii AM, ul. Kilinskiego 1, 15-230 Bialystok, Poland