p53 - tumor suppressor gene

• Authors: B. Schlichtholz
• Languages of publication: PL

Abstracts

EN

The structure of p53 tumor suppressor gene and molecular mechanisms of p53 function are characterized.The effects of the p53 protein on gene transcription, control of the cell cycle, DNA repair and synthesis, cell differentiation, and progrsmmed cell death are discussed.Besides clinical implication of inactivation of the p53 gene in the pathogenesis, diagnosis, and therapy of human cancer are mentioned.

Keywords

EN

CELL DIFFERENTIATION; PROGRAMMED CELL DEATH; TRANSCRIPTION; TUMOR SUPPRESSOR GENE

Discipline

• BIOTECHNOLOGY: BIOTECHNOLOGY

• Publisher: Committee of Biotechnology, Polish Academy of Sciences
• Journal: Biotechnologia
• Year: 1995
• Issue: 3
• Pages: 91-103

Contributors

author

B. Schlichtholz

• Document Type: article
• Publication order reference: B.Schlichtholz