The role of free radicals in pathogenesis of the insulin dependent diabetes mellitus (IDDM)

• Authors: K. Komosinska , K. Olczyk
• Languages of publication: PL

Abstracts

EN

The role of free radicals as well as cytokines (IL-1, tumor necrosis factor alpha, interferon gamma) and nitric oxide in the immune-mediated processes leading to the beta-cell destruction during IDDM is described.It is also pointed that the excess of IL-1ra in relation to IL-1 prevents IL-1 toxicity to beta-cells.

Keywords

EN

CYTOKINE; DIABETES MELLITUS; FREE RADICAL; INSULIN DEPENDENT

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 1995
• Volume: 49
• Issue: 6
• Pages: 733-746

Contributors

author

K. Komosinska

author

K. Olczyk

• Document Type: article
• Publication order reference: K.Komosinska