Subfertile couple with t(4;22)(q23;q11.2)

• Authors: M. Srebniak , L. Popowska , A. Wawrzkiewicz-Witkowska , A. Tomaszewska , W. Kazmierczak
• Languages of publication: EN

Abstracts

EN

A couple was referred for cytogenetic examination due to idiopathic miscarriages. The proband proved to be a carrier of chromosomal translocation and her partner's karyotype was found to be normal. The karyotype of the proband is 46,XX,t(4;22)(q23;q11.2) and can be regarded as a reason of fertility problems in the investigated couple. The risk of further miscarriages is high, but the risk of a progeny with abnormal karyotype is rather low, as the progeny would probably have lethal imbalances.

Keywords

EN

INFERTILITY; MISCARRIAGE; TRANSLOCATION

Discipline

• GENETICS: GENETICS

• Publisher: Institute of Plant Genetics, Polish Academy of Sciences
• Journal: Journal of Applied Genetics
• Year: 2005
• Volume: 46
• Issue: 3
• Pages: 333-336

Contributors

author

M. Srebniak

author

L. Popowska

author

A. Wawrzkiewicz-Witkowska

author

A. Tomaszewska

author

W. Kazmierczak

• Document Type: REPORT
• Publication order reference: M. Srebniak, Department of Medical Genetics, The Medical University of Silesia, ul. Jedno?ci 2, 41-208 Sosnowiec, Poland