Uncovering the differences between T cell tolerance and immunity

• Authors: A.T. Vella
• Languages of publication: EN

Abstracts

EN

In the last two decades T cell function has been analyzed in vitro from many different angles with a great deal of attention dedicated to the basic requirements of activation. During this time a compendium of information has been collected and has proven to be invaluable. Paradoxically very little is known about T cell activation and function in vivo. In the last decade a number of models have been developed which allow the tracking of Ag-activated T cells in vivo and these studies have been instrumental in advancing the field of T cell biology. In particular, a new and emerging paradigm of T cell immunity is evolving.

Keywords

EN

ACTIVATION; IMMUNE MEMORY; IMMUNITY; T CELL

Discipline

• IMMUNOLOGY: IMMUNOLOGY

• Publisher: Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences
• Journal: Archivum Immunologiae et Therapiae Experimentalis
• Year: 2000
• Volume: 48
• Issue: 5
• Pages: 331-338

Contributors

author

A.T. Vella

• Document Type: REVIEW
• Publication order reference: A.T. Vella, Department of Microbiology, Oregon State University, Corvallis, Oregon, USA