Are there different mechanisms of synchronization in the course of spike-wave discharges (SWDs) burst development in WAG/Rij rats?

• Authors: L.S. Godlevsky , G.N. Vostrov , E.V. Kobolev , Luijtelaar E.L.J.M. van_ , A.M.L. Coenen , M.L. Iorhachova , V.A. Pereverzev , I.V. Smirnov
• Languages of publication: EN

Abstracts

EN

In WAG/Rij rats the pair linear correlation ?r' was calculated for bipolar recordings in fronto-temporal, fronto-occipital and occipito-temporal zones of both hemispheres as well as in paleocerebellar cortex (culmen). It was shown that development of SWD bursts resulted in interhemispheric decreases of correlation between the right occipito-temporal cortical region on one side, and left fronto-temporal on the contralateral side. Towards the end of SWD, we found an increased interhemispheric correlation between left fronto-temporal and right fronto-occipital cortical zones, as well as, between both fronto-temporal zones. Paleocerebellum correlates at a weak to moderate level during different periods of SWD burst generation.

Keywords

EN

EPILEPSY; NEOCORTEX; PALEOCEREBELLUM

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Publisher: Marceli Nencki Institute of Experimental Biology, Polish Academy of Sciences
• Journal: Acta Neurobiologiae Experimentalis
• Year: 2006
• Volume: 66
• Issue: 3
• Pages: 189-194

Contributors

author

L.S. Godlevsky

author

G.N. Vostrov

author

E.V. Kobolev

author

Luijtelaar E.L.J.M. van_

author

A.M.L. Coenen

author

M.L. Iorhachova

author

V.A. Pereverzev

author

I.V. Smirnov

• Document Type: ARTICLE
• Publication order reference: Leonid S. Godlevsky, Odessa State Medical University