No incidence of DUMPS carriers in Polish dairy cattle

• Authors: S. Kaminski , G. Grzybowski , P. Prusak , A. Rusc
• Languages of publication: EN

Abstracts

EN

DUMPS (Deficiency of Uridine Monophosphate Synthase) is a hereditary recessive disorder in Holstein cattle causing early embryo mortality during its implantation in the uterus. The only way to avoid the economic losses is early detection of DUMPS carriers. Because American Holstein semen has been intensively imported to Poland since 1970, there was a risk that DUMPS could have spread in Polish dairy cattle. In our study, 2209 dairy cattle of the Polish Holstein breed have been screened by the DNA test. The dominant group was young bulls entering the testing program (1171) and proven bulls (781). They represented all sires entering Polish breeding programs between 1999 and 2003. Also, 257 sire dams were included in the screening program. No DUMPS carrier has been found. Our results then indicate that the population of dairy cattle reared in Poland is free from DUMPS. Because of the economical significance of the DUMPS mutation and its recessive mode of inheritance, attention has to be paid to any case of a bull having in his origin any known DUMPS carrier. Such a bull should be tested and if positive eliminated from the active population. Also, young bulls (testing bulls) should be screened for DUMPS if in their progeny a high incidence of embryo mortality is observed and their genealogy cannot exclude their relatedness to any DUMPS carriers.

Keywords

EN

DAIRY CATTLE; DUMPS MUTATION; GENETIC SCREENING

Discipline

• GENETICS: GENETICS

• Publisher: Institute of Plant Genetics, Polish Academy of Sciences
• Journal: Journal of Applied Genetics
• Year: 2005
• Volume: 46
• Issue: 4
• Pages: 395-397

Contributors

author

S. Kaminski

author

G. Grzybowski

author

P. Prusak

author

A. Rusc

• Document Type: SHORT COMMUNICA
• Publication order reference: S. Kaminski, Department of Animal Genetics, University of Warmia and Mazury, M. Oczapowskiego 5, 10-957 Olsztyn, Poland