Lack of carriers of citrullinaemia and DUMPS in Indian Holstein cattle

• Authors: R.K. Patel , K.M. Singh , K.J. Soni , J.B. Chauhan , Rao K.R.S. Sambasiva
• Languages of publication: EN

Abstracts

EN

The present study investigated the occurrence of 2 autosomal recessive genetic diseases, bovine citrullinaemia and deficiency of uridine monophosphate synthase (DUMPS), in Indian Holstein cattle. The polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis was performed on a group of 642 animals, mainly HF and HF crossbred cattle, to identify carriers of these diseases. None of the animals were carriers of citrullinaemia or DUMPS. It is possible that with the mounting selection pressure, the international gene pool may diminish, and consequently the risk of dissemination of inherited defects will increase. It is therefore recommended to screen breeding bulls for their breed-specific genetic diseases before they are inducted in artificial insemination programmes, to minimize the risk.

Keywords

EN

CITRULLINAEMIA; HOLSTEIN CATTLE; PCR-RFLP

Discipline

• GENETICS: GENETICS

• Publisher: Institute of Plant Genetics, Polish Academy of Sciences
• Journal: Journal of Applied Genetics
• Year: 2006
• Volume: 47
• Issue: 3
• Pages: 239-242

Contributors

author

R.K. Patel

author

K.M. Singh

author

K.J. Soni

author

J.B. Chauhan

author

Rao K.R.S. Sambasiva

• Document Type: ARTICLE
• Publication order reference: R.K Patel, Scientist ? III (R&D ? Biotechnology), National Dairy Development Board, Anand ? 388 001 India