New method of chemical synthesis of O-linked glycopeptides

• Authors: R.L. Polt , L. Szabo , J. Ramza
• Languages of publication: PL

Abstracts

EN

The diphenylketone Shiff - base appeared to be a very good protection for amino groups of serine and threonine for glycosylation reaction. O-glycosides of these aminoacids with different monosaccharides, aminosugars and deoxysugars were obtained with excelent yield and very high stereoselectivity. Products of glycosylation reactions were used as building blocks for solid phase glycopeptide synthesis.

Keywords

EN

GLYCOPEPTIDE; GLYCOPROTEIN

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 1996
• Volume: 50
• Issue: 5
• Pages: 493-503

Contributors

author

R.L. Polt

author

L. Szabo

author

J. Ramza

• Document Type: article
• Publication order reference: J.Ramza, ul. Rydygiera 8, 01-793 Warszawa, Poland